Introduction: Skin disease caused by exposure to the chemicals is one of the major health-related problems in the workplaces. This study has done to prioritize the strategies for skin exposure with chemical in a painting company. Material and Method: In this analytical cross-sectional study 7 criteria and 8 selection control methods were initially chosen by surveying the existing records and through the assessments of expert panel and checking the result of previous studies. Subsequently, control strategies were prioritized according to the criteria using Fuzzy Analytical Hierarchy process & TOPSIS. Result: Results of the paired comparison showed that the safety of the control strategy (w=0. 298) and it’ s up to date (w=0. 0138) were the most and least important criteria for skin control strategies. Among skin control strategies for chemical exposure, the highest and lowest importance were for training (w=0. 817) and work-rest schedule (w=0. 233), respectively. Conclusion: In this study, training was determined as the best control strategies for skin chemical exposure in the studied painting company according to the investigated criteria. This decision-making process could be applied for promotion of the skin health among workers.