Background: Previous studies showed that managed surveillance and treatment have a considerable effect on decreasing the mortality and morbidity in head trauma patients. But there isn’t a validated guideline in Iran.Thus, the aim of this study was nativation of diagnosis, treatment and clinical prevention of head trauma guideline for using in Isfahan hospitals.Methods: In a cross sectional study, 6 validated guidelines for management of head trauma were studied and the most important head lines were extracted and then, attitude of resident and attends of treatment groups including neurosurgery, anesthesia and emergency medicine was given and the agreement between treatment group and guideline was analyzed.Findings: In this study, six guidelines were studied and attitude of 78 persons of treatment group of head trauma including 30 persons from emergency medicine ward, 28 persons from neurosurgery ward and 20 persons from anesthesiology ward were compared with the guidelines. The mean±SD of enter viewed staff was 15.0±2.7 (range: 8-20) and based on that, attitude of 14 (17.9%) had excellent agreement, 34 (43.6%) had good agreement, 27 (34.6%) had acceptable agreement and 3 (3.8%) had weak agreement with the guide lines.Conclusion: According to the results of this study, management of head trauma treatment is not programmed and in several stages was not approved and this practice may lead to higher risk of morbidity and mortality and additive hospital cost. So, treatment methods, surveillance and treatment of head trauma patients must be revised.