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سال:1393 | دوره:19 | شماره:3 |تعداد مقالات:10

Background: Irritable bowel syndrome (IBS) is identified by chronic abdominal pain and altered bowel habits in the absence of organic etiology. Premature ejaculation is the most common male sexual disorder. We aimed to evaluate the frequency of premature ejaculation disorders in patients with IBS referred to a gastrointestinal clinic in Rafsanjan, Iran, in 2012.Materials and Methods: Of all the men referred to the gastrointestinal clinic, those with a diagnosis of IBS (based on Rome-II criteria)were interviewed. Premature ejaculation disorder based on DSM-IV-TR criteria was documented by psychiatry interview. History of psychiatric diseases of the patients and their family were assessed by interview done by a psychiatrist. The data were analyzed by using SPSS software (version 16). Descriptive statistics, inferential tests, and Chi-square test were used for analyses.Results: One hundred and fifty two men with IBS were evaluated. Based on the Rome-II criteria, 89(58.6%) patients were suffering from premature ejaculation disorder. Fifty nine (38.8%) patients expressed drug addiction. Sixty eight (44.7%) had a history of psychiatric disease in the past and 84 (55.3%) patients stated they were not suffering from any psychiatric diseases. Forty six (30.3%) patients had a history of psychiatric disease in their family, and 106 (69.7%) did not have any history of psychiatric disorder. High frequency of premature ejaculation in patients with IBS with a family history of psychiatric disorder and severe stress during the past year suggested that there was a relationship between factors contributing to psychiatric disorders (neurotransmitters, environmental factors, and genetics) and premature ejaculation.Conclusion: Premature ejaculation is more common in patients with IBS. Drug abuse, family history of psychiatric disorder, and severe emotional stress during the past year, significantly increase the frequency of premature ejaculation.

Background: There were few studies reporting simultaneous presence of Helicobacter pylori (H. pylori) in stomach and gallbladder stones, most of which have been conducted on bile specimens or gallbladder tissues. Presence of a chronic inflammatory disease may contribute to gall stone formation through production of inflammatory cytokines. Chronic active gastritis due to H.pylori may contribute to lithogenesis in gallbladder. In this regard, the present study aimed to investigate the frequency and association of gastric H.pylori infection and gallstones in patients who were undergoing upper endoscopy in a teaching hospital.Materials and Methods: In this case-control study patients presenting with dyspeptic symptoms who underwent upper endoscopy during 2008-2012 in Shahid Beheshti Hospital of Babol, northern Iran were enrolled, 72 patients with and 136 patients without gallstones were assigned as the case and control groups, respectively. Patients with history of gastric surgery PPI, and antibiotic consumption four weeks before endoscopy were excluded from the study. Two biopsies were obtained from gastric antrum and body of each patient in both groups and examined histologically for gastritis and the presence of H. pylori. Then, endoscopic, histological and demographic features (age, gender, BMI, smoking, NSAID) in these two groups were compared. The SPSS software (version 18) was used for analysis. P-value of <0.05 was considered as statistically significant.Results: Fifty-two (72.2%) and 98 (72.1%) of all patients with and without gallstone were female, respectively (p=0.7). The mean age of patients with gallstone was 51.8±14 years, while it was 51.1±15 years in patients without gallstone (p = 0.9). H.pylori was detected in gastric mucosa of 31(43.1%) and 45 (33.8%) cases with and without gallstone, respectively. Although H.pylori infection was higher in patients with gallstones, the difference was not statistically significant (p =0.19). In the group with gallstones, 21 (29.2%) patients revealed severe gastritis, and in those without gallstones, 17 (12.5%) patients were found with severe gastritis. This difference was statistically significant (p =0.003, OR=2.88, CI: 1.41-5.91).Conclusion: This study demonstrates that patients with severe H.pylori induced gastritis are likely to have gallstone in comparison with mild gastritis. The frequency of H. pylori infection in patients with gallstones is more than those without gallstones.

Pylephlebitis was a rare condition with high rates of morbidity and mortality. It is defined as thrombosis of the hepatic and portal veins that complicates intra-abdominal infections. however prompt diagnosis plays a significant role in the treatment of pylephlebitis and the disorder can be diagnosed by means of ultrasound or contrast tomography, it was often missed due to nonspecific clinical presentation including fever, abdominal discomfort and fatigue. When it came to treatment, despite controversies about the use of anticoagulants, administration of antibiotics and anticoagulants was still the mainstay of treatment. In this report, we described a 67-year-old man with chief complaint of bouts of high fevers and mild abdominal tenderness located in right lower quadrant. The patient suffered from pylephlebitis secondary to cecal diverticulitis. Our patient’s symptoms did not resolve with antibiotic therapy thus he had surgical resection of the infection focus and received anticoagulation. To put in a nutshell, as early diagnosis and treatment are essential steps for proper management of pylephlebitis and preventing its adverse complications, it is of high importance to keep this differential diagnosis in mind in patients with abdominal sepsis sings.