PHYTOCHEMICAL INVESTIGATION OF WITHANIA COAGULANS (STOCKS) DUNAL IN NATURAL HABITS OF SISTAN AND BALUCHESTAN PROVINCE OF IRAN

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VALIZADEH M.; BAGHERI A.; VALIZADEH J.; MIRJALILI M.H.

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Journal: IRANIAN JOURNAL OF MEDICINAL AND AROMATIC PLANTS Year:2015 | Volume:31 | Issue:3 (71) Page(s): 406-417

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Title

PHYTOCHEMICAL INVESTIGATION OF WITHANIA COAGULANS (STOCKS) DUNAL IN NATURAL HABITS OF SISTAN AND BALUCHESTAN PROVINCE OF IRAN

Author(s)

VALIZADEH M. | BAGHERI A. | VALIZADEH J. | MIRJALILI M.H. | Issue Writer Certificate

Keywords

PHYTOCHEMICAL INVESTIGATIONQ1

WITHANIA COAGULANS (STOCKS) DUNALQ2

SISTAN AND BALUCHESTANQ1

WITHAFERIN A.Q2

Abstract

Withania coagulans (Stocks) Dunal (fam. Solanaceae) is a multipurpose medicinal plant, mainly distributed in southeastern parts of SISTAN AND BALUCHESTAN province. The important medicinal properties of W. coagulans are attributed to the presence of steroidal lactones called withanolides. Among withanoloids, WITHAFERIN A.is an important phytoconstituent showing antitumor, ant iangiogenesis and apoptosis induction properties. This study was aimed to investigate the variability of phytochemical composition of Withania coagulans roots. Twenty accessions of W. coagulans roots, collected from different natural habits of SISTAN AND BALUCHESTAN province, were used in the present study. The WITHAFERIN A.was assayed through thin layer chromatography (TLC) method and phytochemical estimation was carried out by standard methodologies to detect the presence of secondary metabolites, like total phenol, flavonoids and anthocyanin. Our findings revealed that WITHAFERIN A.was found in all accessions collected from different natural habits. The photochemical investigation showed the presence of flavonoids (5.70-6.50%), anthocyanin (4.51-9.51mmol/g) and total phenol (14.91- 23.7μgGAE/mgD.W), varying significantly among the habitats (p<0.05). In the present study, TLC analysis confirms the exsistance of WITHAFERIN A.in all W. coagulans accessions as well as the potential of SISTAN AND BALUCHESTAN natural habits to produce this valuable component. However, the root extracts of W. coagulans, growing in natural habitats of Iran, have higher phenolic content. Hence, it can be used as a source of natural components for the pharmaceutical and food industries.

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APA: Copy

VALIZADEH, M., BAGHERI, A., VALIZADEH, J., & MIRJALILI, M.H.. (2015). PHYTOCHEMICAL INVESTIGATION OF WITHANIA COAGULANS (STOCKS) DUNAL IN NATURAL HABITS OF SISTAN AND BALUCHESTAN PROVINCE OF IRAN. IRANIAN JOURNAL OF MEDICINAL AND AROMATIC PLANTS, 31(3 (71)), 406-417. SID. https://sid.ir/paper/105016/en

Vancouver: Copy

VALIZADEH M., BAGHERI A., VALIZADEH J., MIRJALILI M.H.. PHYTOCHEMICAL INVESTIGATION OF WITHANIA COAGULANS (STOCKS) DUNAL IN NATURAL HABITS OF SISTAN AND BALUCHESTAN PROVINCE OF IRAN. IRANIAN JOURNAL OF MEDICINAL AND AROMATIC PLANTS[Internet]. 2015;31(3 (71)):406-417. Available from: https://sid.ir/paper/105016/en

IEEE: Copy

M. VALIZADEH, A. BAGHERI, J. VALIZADEH, and M.H. MIRJALILI, “PHYTOCHEMICAL INVESTIGATION OF WITHANIA COAGULANS (STOCKS) DUNAL IN NATURAL HABITS OF SISTAN AND BALUCHESTAN PROVINCE OF IRAN,” IRANIAN JOURNAL OF MEDICINAL AND AROMATIC PLANTS, vol. 31, no. 3 (71), pp. 406–417, 2015, [Online]. Available: https://sid.ir/paper/105016/en

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