STUDY OF ANTI-INFLAMMATORY EFFECT OF AQUEOUS AND HEXANE EXTRACT OF APIUM GRAVEOLENS L. IN MICE

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RAMEZANI MINA; NASRI SIMA; YASA N.

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Paper Information

Journal: IRANIAN JOURNAL OF MEDICINAL AND AROMATIC PLANTS Year:2009 | Volume:24 | Issue:4 (42) Page(s): 437-443

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Title

STUDY OF ANTI-INFLAMMATORY EFFECT OF AQUEOUS AND HEXANE EXTRACT OF APIUM GRAVEOLENS L. IN MICE

Author(s)

RAMEZANI MINA | NASRI SIMA | YASA N. | Issue Writer Certificate

Keywords

APIUM GRAVEOLENS L.Q3

AQUEOUS EXTRACTQ2

HEXANE EXTRACTQ3

ANTI-INFLAMMATORYQ3

Abstract

On the basis of ANTI-INFLAMMATORY effect of APIUM GRAVEOLENS L. in traditionally herbal medicine, in present study aqueous and HEXANE EXTRACTs were evaluated to find effective fractions. For induction of inflammation xylene-induced ear edema were used. Male NMRI mice were divided into three groups: positive control (dexamethason 15mg/kg), negative control (normal saline), and experimental groups. Experimental groups were injected by 100, 200, 300, 400 and 500mg/kg of aqueous and HEXANE EXTRACTs intraperitoneally. To find effective constituents of extract, TLC (thin layer chromatography) was performed. Results have shown significant ANTI-INFLAMMATORY effects of both extracts (100-500mg/kg doses) with control, and there was not significant difference with dexamethason. Data show potent ANTI-INFLAMMATORY effects of aqueous and HEXANE EXTRACTs even with low doses which may be due to existence of flavonoid, phthalid and coumarins in Apium graveolens seeds.

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APA: Copy

RAMEZANI, MINA, NASRI, SIMA, & YASA, N.. (2009). STUDY OF ANTI-INFLAMMATORY EFFECT OF AQUEOUS AND HEXANE EXTRACT OF APIUM GRAVEOLENS L. IN MICE. IRANIAN JOURNAL OF MEDICINAL AND AROMATIC PLANTS, 24(4 (42)), 437-443. SID. https://sid.ir/paper/105095/en

Vancouver: Copy

RAMEZANI MINA, NASRI SIMA, YASA N.. STUDY OF ANTI-INFLAMMATORY EFFECT OF AQUEOUS AND HEXANE EXTRACT OF APIUM GRAVEOLENS L. IN MICE. IRANIAN JOURNAL OF MEDICINAL AND AROMATIC PLANTS[Internet]. 2009;24(4 (42)):437-443. Available from: https://sid.ir/paper/105095/en

IEEE: Copy

MINA RAMEZANI, SIMA NASRI, and N. YASA, “STUDY OF ANTI-INFLAMMATORY EFFECT OF AQUEOUS AND HEXANE EXTRACT OF APIUM GRAVEOLENS L. IN MICE,” IRANIAN JOURNAL OF MEDICINAL AND AROMATIC PLANTS, vol. 24, no. 4 (42), pp. 437–443, 2009, [Online]. Available: https://sid.ir/paper/105095/en

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