COMPARATIVE STUDY ON EFFECT OF PENICILLIN G, OXYTETRACYCLIN AND ENROFLOXACIN ANTIBIOTICS ON NEUTROPHIL FUNCTION OF THE PERIPHERAL BLOOD OF SHEEP (IN VITRO)

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

REZAPOUR A.

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: VETERINARY CLINICAL PATHOLOGY (VETERINARY JOURNAL TABRIZ) Year:2011 | Volume:5 | Issue:2 (18) Page(s): 1169-1173

Download Full-Text

Persian Verion

View:

3,217

Download:

Cites:

Information Journal Paper

Title

COMPARATIVE STUDY ON EFFECT OF PENICILLIN G, OXYTETRACYCLIN AND ENROFLOXACIN ANTIBIOTICS ON NEUTROPHIL FUNCTION OF THE PERIPHERAL BLOOD OF SHEEP (IN VITRO)

Author(s)

REZAPOUR A. | Issue Writer Certificate

Keywords

ENROFLOXACINQ2

NEUTROPHIL FUNCTIONQ2

NITROBLUE TETRAZOLIUM REDUCTIONQ2

OXYTETRACYCLINQ2

PENICILLIN GQ2

PHAGOCYTOSISQ2

Abstract

The aim of this study was in vitro evaluation of the effects of some common antibiotics in treatment of microbial infections in sheep on in vitro function of neutrophils. Purified neutrophils of sheep incubated with different levels of OXYTETRACYCLIN and ENROFLOXACIN (0, 1, 10, 100 and 200 mcg/ml) and PENICILLIN G (0, 250, 500, 1000, 2000 and 4000 IU/ml) antibiotics for one hour in room temperature. PHAGOCYTOSIS and nitro-blue tetrazolium reduction (NBT) percentage tested in every sample. Mixed model (REML) was used as a statistical procedure. Data means compared by LSMEAN and p<0.01 considered statistically significant. The results showed that LSMEAN of PHAGOCYTOSIS and NBT percentage were not statistically significant in different levels of PENICILLIN G. PHAGOCYTOSIS and NBT percentage were statistically non-significant comparing to control group up to 10 and 200 mcg/ml (respectively) but, PHAGOCYTOSIS percentage from 100 mcg/ml to upper level and NBT percentage in 400 mcg/ml level were statistically significant (p<0.01). LSMEAN of PHAGOCYTOSIS percentage in 100 mcg/ml (and upper) decreased dramatically for OXYTETRACYCLIN (p<0.0001). With the exception of 0 and 1 mcg/ml of OXYTETRACYCLIN, other levels of OXYTETRACYCLIN decreased NBT percentage (p<0.0001). Then according to the negative effects of those mentioned antibiotics on NEUTROPHIL FUNCTION, we can introduce PENICILLIN G as an antibiotic with minimum inhibitory effects on NEUTROPHIL FUNCTIONs (in vitro). But range of non-risk level for OXYTETRACYCLIN on NEUTROPHIL FUNCTION was<1 mcg/ml (that may be had not treating effect) then in this view, this drug is not recommended and it shouldn’t be a number one antibiotic.

Cites

No record.

References

No record.

Cite

APA: Copy

REZAPOUR, A.. (2011). COMPARATIVE STUDY ON EFFECT OF PENICILLIN G, OXYTETRACYCLIN AND ENROFLOXACIN ANTIBIOTICS ON NEUTROPHIL FUNCTION OF THE PERIPHERAL BLOOD OF SHEEP (IN VITRO). VETERINARY CLINICAL PATHOLOGY (VETERINARY JOURNAL TABRIZ), 5(2 (18)), 1169-1173. SID. https://sid.ir/paper/183225/en

Vancouver: Copy

REZAPOUR A.. COMPARATIVE STUDY ON EFFECT OF PENICILLIN G, OXYTETRACYCLIN AND ENROFLOXACIN ANTIBIOTICS ON NEUTROPHIL FUNCTION OF THE PERIPHERAL BLOOD OF SHEEP (IN VITRO). VETERINARY CLINICAL PATHOLOGY (VETERINARY JOURNAL TABRIZ)[Internet]. 2011;5(2 (18)):1169-1173. Available from: https://sid.ir/paper/183225/en

IEEE: Copy

A. REZAPOUR, “COMPARATIVE STUDY ON EFFECT OF PENICILLIN G, OXYTETRACYCLIN AND ENROFLOXACIN ANTIBIOTICS ON NEUTROPHIL FUNCTION OF THE PERIPHERAL BLOOD OF SHEEP (IN VITRO),” VETERINARY CLINICAL PATHOLOGY (VETERINARY JOURNAL TABRIZ), vol. 5, no. 2 (18), pp. 1169–1173, 2011, [Online]. Available: https://sid.ir/paper/183225/en

Related Journal Papers