THE EFFECT OF FOLIC ACID ON SPERM PARAMETERS ON TESTICULAR ISCHEMIA-REPERFUSION INJURY IN RAT

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

FAKOURI A.; ASGHARI A.; AKBARI GH.

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: JOURNAL OF COMPARATIVE PATHOBIOLOGY IRAN Year:2018 | Volume:14 (NEW) | Issue:4 (59) Page(s): 2353-2362

Download Full-Text

Persian Verion

View:

957

Download:

Cites:

Information Journal Paper

Title

THE EFFECT OF FOLIC ACID ON SPERM PARAMETERS ON TESTICULAR ISCHEMIA-REPERFUSION INJURY IN RAT

Author(s)

FAKOURI A. | ASGHARI A. | AKBARI GH. | Issue Writer Certificate

Keywords

TESTICLEQ2

ISCHEMIA/ REPERFUSIONQ1

FOLIC ACIDQ2

RATQ2

Abstract

Ischemia reperfusion definition is the return of blood to ischemia tissue. In this study, the effects of FOLIC ACID as a drug, on testicular function in adult RATs were studied after induction ischemia/reperfusion. In this study, 36 male Wistar RATs, the weight range between 250-300gr, were selected and divided into 6 equal groups randomly. The Control group: The Group has not received any medication and every day the same volume of distilled water was administered like other groups and after a week the abdominal cavity was opened and the left TESTICLE was removed. The Sham group: The group has not received any medication and every day the same volume of distilled water were administered like other groups and after a week the abdominal cavity was opened and after removal of TESTICLE from the scrotum and replacing, the abdominal cavity reclosed. I/R group: The group has not received any medication until indication of ischemia/reperfusion and every day the same volume of distilled water were administered like other groups and after 1 week the abdominal cavity was opened, and left testicular vein and artery was constricted for 1 hour thus the experimental ischemia reperfusion was induced and after 24 hour, the abdomen was opened and the left testis along with the left epididymis was extracted.4th, 5th, 6th group: these groups were administered orally with (2, 5 & 10 mg/kg) of FOLIC ACID for 1 week, the abdominal cavity was opened, and left testicular vein and artery was constricted for 1 hour thus the experimental ischemia reperfusion was induced and after 24 hours the abdomen was opened and the left testis along with the left epididymis was extracted.After the RATs were euthanized the epididymis were removed and then by scissors were cut into small pieces to allow sperm comfortable out there and immediately placed in 5 ml HBSS environment and for 20 minutes on a hot plate was incubated at 37°C and then evaluate sperm parameters (sperm count and sperm vitality and motility) were performed. The data were statistically analyzed and statistics on the percentage of progressive motility, sperm viability and sperm concentration per unit volume of FOLIC ACID showed significant difference (p<0.05) compared to I/R group. Based on the results obtained, it seems FOLIC ACID can behave appropriate and acceptable effects to Prevention of Ischemia-reperfusion injury in RAT testis.

Cites

No record.

References

No record.

Cite

APA: Copy

FAKOURI, A., ASGHARI, A., & AKBARI, GH.. (2018). THE EFFECT OF FOLIC ACID ON SPERM PARAMETERS ON TESTICULAR ISCHEMIA-REPERFUSION INJURY IN RAT. JOURNAL OF COMPARATIVE PATHOBIOLOGY IRAN, 14 (NEW)(4 (59)), 2353-2362. SID. https://sid.ir/paper/197472/en

Vancouver: Copy

FAKOURI A., ASGHARI A., AKBARI GH.. THE EFFECT OF FOLIC ACID ON SPERM PARAMETERS ON TESTICULAR ISCHEMIA-REPERFUSION INJURY IN RAT. JOURNAL OF COMPARATIVE PATHOBIOLOGY IRAN[Internet]. 2018;14 (NEW)(4 (59)):2353-2362. Available from: https://sid.ir/paper/197472/en

IEEE: Copy

A. FAKOURI, A. ASGHARI, and GH. AKBARI, “THE EFFECT OF FOLIC ACID ON SPERM PARAMETERS ON TESTICULAR ISCHEMIA-REPERFUSION INJURY IN RAT,” JOURNAL OF COMPARATIVE PATHOBIOLOGY IRAN, vol. 14 (NEW), no. 4 (59), pp. 2353–2362, 2018, [Online]. Available: https://sid.ir/paper/197472/en

Related Journal Papers