POLYMORPHISM OF MYOSTATIN GENE AND ITS ASSOCIATION WITH GROWTH TRAITS INRAEINI CASHMERE GOATS

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SANJARI ELAHE; ZIEAADINI MAHDIYEH; ASADI FOZI MASOUD; ESMAILIZADEH KOSHKOIYEH ALI

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Journal: Journal of Animal Production Year:2018 | Volume:20 | Issue:3 Page(s): 365-372

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Title

POLYMORPHISM OF MYOSTATIN GENE AND ITS ASSOCIATION WITH GROWTH TRAITS INRAEINI CASHMERE GOATS

Author(s)

SANJARI ELAHE | ZIEAADINI MAHDIYEH | ASADI FOZI MASOUD | ESMAILIZADEH KOSHKOIYEH ALI | Issue Writer Certificate

Keywords

DOUBLE-MUSCLINGQ1

EXONQ1

MUSCLE GROWTHQ1

MOLECULAR MARKERQ1

MUTATIONQ1

Abstract

This wok was conducted to identify polymorphisms in the region of the EXON 1 in 5'UTR of myostatin gene and theirrelationships with the growth traits in Raeini cashmere goats. Myostatin gene has been identified as a factor causing aphenotype known as DOUBLE-MUSCLING in which a series of MUTATIONs render the gene inactivity; therefore, able toincrease MUSCLE GROWTH. Blood samples were randomly taken from 150 Raeini cashmere goats. Total genomic DNAwas extracted and a 701 bp fragment was amplified from the EXON 1 of myostatin gene using PCR-RFLP method. Theanalysis of band patterns indicated three genotypes including AA, AB and BB with frequencies of 0. 56, 0. 33 and0. 11, respectively. The A and B alleles had a frequency of 0. 72 and 0. 28, respectively. The analysis of additive anddominance gene actions revealed that the effect of the myostatin gene on growth traits and body size of Raeinicashmere goats is via the dominance mechanism. The results showed that all growth traits except weaning weightwere significantly associated with the identified polymorphisms, thus this gene can be used as a MOLECULAR MARKER inRaeini cashmere goats breeding.

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APA: Copy

SANJARI, ELAHE, ZIEAADINI, MAHDIYEH, ASADI FOZI, MASOUD, & ESMAILIZADEH KOSHKOIYEH, ALI. (2018). POLYMORPHISM OF MYOSTATIN GENE AND ITS ASSOCIATION WITH GROWTH TRAITS INRAEINI CASHMERE GOATS. JOURNAL OF ANIMAL PRODUCTION (JOURNAL OF AGRICULTURE), 20(3 ), 365-372. SID. https://sid.ir/paper/209099/en

Vancouver: Copy

SANJARI ELAHE, ZIEAADINI MAHDIYEH, ASADI FOZI MASOUD, ESMAILIZADEH KOSHKOIYEH ALI. POLYMORPHISM OF MYOSTATIN GENE AND ITS ASSOCIATION WITH GROWTH TRAITS INRAEINI CASHMERE GOATS. JOURNAL OF ANIMAL PRODUCTION (JOURNAL OF AGRICULTURE)[Internet]. 2018;20(3 ):365-372. Available from: https://sid.ir/paper/209099/en

IEEE: Copy

ELAHE SANJARI, MAHDIYEH ZIEAADINI, MASOUD ASADI FOZI, and ALI ESMAILIZADEH KOSHKOIYEH, “POLYMORPHISM OF MYOSTATIN GENE AND ITS ASSOCIATION WITH GROWTH TRAITS INRAEINI CASHMERE GOATS,” JOURNAL OF ANIMAL PRODUCTION (JOURNAL OF AGRICULTURE), vol. 20, no. 3 , pp. 365–372, 2018, [Online]. Available: https://sid.ir/paper/209099/en

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