DETECTION OF COPY NUMBER VARIATION IN HOLSTEIN CATTLE GENOME BY USING 50K

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

NOSRATI M.; TAHMORESPOUR M.; NASSIRY M.R.

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: JOURNAL OF AGRICULTURAL BIOTECHNOLOGY Year:2014 | Volume:6 | Issue:1 Page(s): 199-214

Download Full-Text

Persian Verion

View:

899

Download:

Cites:

Information Journal Paper

Title

DETECTION OF COPY NUMBER VARIATION IN HOLSTEIN CATTLE GENOME BY USING 50K

Author(s)

NOSRATI M. | TAHMORESPOUR M. | NASSIRY M.R. | Issue Writer Certificate

Keywords

HOLSTEIN CATTLEQ3

CNVQ2

SNPQ2

GENOMEQ2

Abstract

Copy number variation (CNV) is important on biological mechanism. For CNV detection and distribution, three bovine autosomal chromosomes, BTA6, BTA14 and BTA6 that improved for quantitative trait loci (QTL) previously, were investigated. Blood sample we obtained from 580 animals and after DNA extraction the samples were genotyped by Illumina BovineSNP50v2 Bead Chip. Three hundred eighty three samples were remained for further analysis, after correction for signal intensity and GC content. Data were analyzed based on UMD3.1 bovine GENOME assembly for BTA6, BTA14 and BTA20. After filtration 199 CNV were detected (132 losses and 67 gains) with 0.5 CNV per animal and mean and medium of 147.3 kb and 139.4 kb respectively. A proportion of loss to gain was 1.97 fold. The Max and Min Number of CNV detected on BTA6 and BTA20 respectively. The bioinformatics analysis showed CNV region's coverage some part of 77 reference gene in bovine GENOME.These results showed that CNV coverage remarkable part of the three chromosomes that contain several QTL. Because of the influence of CNV on gene dosage and gene structure, it can cause phonotypic variation in quantitative traits, so probably it can be useful on livestock breeding programs.

Cites

No record.

References

No record.

Cite

APA: Copy

NOSRATI, M., TAHMORESPOUR, M., & NASSIRY, M.R.. (2014). DETECTION OF COPY NUMBER VARIATION IN HOLSTEIN CATTLE GENOME BY USING 50K. JOURNAL OF AGRICULTURAL BIOTECHNOLOGY, 6(1), 199-214. SID. https://sid.ir/paper/224537/en

Vancouver: Copy

NOSRATI M., TAHMORESPOUR M., NASSIRY M.R.. DETECTION OF COPY NUMBER VARIATION IN HOLSTEIN CATTLE GENOME BY USING 50K. JOURNAL OF AGRICULTURAL BIOTECHNOLOGY[Internet]. 2014;6(1):199-214. Available from: https://sid.ir/paper/224537/en

IEEE: Copy

M. NOSRATI, M. TAHMORESPOUR, and M.R. NASSIRY, “DETECTION OF COPY NUMBER VARIATION IN HOLSTEIN CATTLE GENOME BY USING 50K,” JOURNAL OF AGRICULTURAL BIOTECHNOLOGY, vol. 6, no. 1, pp. 199–214, 2014, [Online]. Available: https://sid.ir/paper/224537/en

Related Journal Papers