The Embryotoxicity of Some Phenol Derivatives on Zebrafish, Danio rerio

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Ceylan Zeynep; Sisman Turgay; Dane Hatice; Adil seymanur

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Journal: CASPIAN JOURNAL OF ENVIRONMENTAL SCIENCES (CJES) Year:2019 | Volume:17 | Issue:1 Page(s): 11-22

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Information Journal Paper

Title

The Embryotoxicity of Some Phenol Derivatives on Zebrafish, Danio rerio

Author(s)

Ceylan Zeynep | Sisman Turgay | Dane Hatice | Adil seymanur | Issue Writer Certificate

Keywords

Substituted phenolQ3

2-ChlorophenolQ3

2Q3

4-DichlorophenolQ3

zebrafishQ3

embryotoxicityQ3

Abstract

The existence of toxicants in ecosystems has been increased dramatically in recent years, especially in aquatic environments. Phenols and chlorinated phenol derivatives are toxic industrial compounds. Phenols and derivatives are known to be environmental contaminants. In the present study, 2, 4-Dichlorophenol, 2-Chlorophenol and Substituted phenol were tested for embryotoxicity and mortality in a four-day period using zebrafish, Danio rerio embryos. Tested phenol derivatives caused teratogenicity and embryo mortality in the embryos. The semi static 48-h LC50 (median lethal concentration) value for Substituted-phenol was 13. 850 mg L-1; the corresponding values for 2-Chlorophenol and 2, 4-Dichlorophenol were 8. 378 mg L-1 and 6. 558 mg L-1, respectively. The endpoints are incomplete eyes, head and tail, heart and chorda deformity, yolk sac edema, tail curvature, shrunken eyes, lordosis, delayed hatching, weak pigmentation, heart edema and non-pigmentation after exposure to the compounds. 2, 4-Dichlorophenol was found to be more toxic than the others. This paper is the first to describe the relative toxicity of a suite of phenols in the early life stages of zebrafish.

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APA: Copy

Ceylan, Zeynep, Sisman, Turgay, Dane, Hatice, & Adil, seymanur. (2019). The Embryotoxicity of Some Phenol Derivatives on Zebrafish, Danio rerio. CASPIAN JOURNAL OF ENVIRONMENTAL SCIENCES (CJES), 17(1 ), 11-22. SID. https://sid.ir/paper/240748/en

Vancouver: Copy

Ceylan Zeynep, Sisman Turgay, Dane Hatice, Adil seymanur. The Embryotoxicity of Some Phenol Derivatives on Zebrafish, Danio rerio. CASPIAN JOURNAL OF ENVIRONMENTAL SCIENCES (CJES)[Internet]. 2019;17(1 ):11-22. Available from: https://sid.ir/paper/240748/en

IEEE: Copy

Zeynep Ceylan, Turgay Sisman, Hatice Dane, and seymanur Adil, “The Embryotoxicity of Some Phenol Derivatives on Zebrafish, Danio rerio,” CASPIAN JOURNAL OF ENVIRONMENTAL SCIENCES (CJES), vol. 17, no. 1 , pp. 11–22, 2019, [Online]. Available: https://sid.ir/paper/240748/en

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