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Information Journal Paper

Title

Immune response and enzymatic activities of broiler chicks under cold stress to nitroglycerin

Pages

  205-216

Abstract

 This experiment was conducted to evaluate the effect of addition of nitroglycerin (NG) slow release drug on prevention of ascites syndrome in broiler chickens. A total of 500 male broiler chicks at 7 day of age were used in a completely randomized design with 5 treatments, 5 replicates and 20 chicks per each replication. The experimental treatments included: 1) positive control group (without induction of ascites and without addition of NG); 2) negative control group (induction of ascites without adding NG), and treatments 3, 4 and 5, including induction of ascites with 5, 10 and 20 mg NG /kg diet, respectively. In order to induce cold stress, the rearing house temperature was fixed at 15 o C from 15 until 42 day of age. The humeral and cellular immune responses as well as blood serum enzyme concentrations were evaluated. The results showed that cold stress significantly reduced the relative weights of spleen and thymus (P<0. 05) but had no significant effect on relative weight of bursa of Fabricius gland. The utilization of NG significantly increased the relative weights of spleen and thymus (P<0. 05). The immunoglobulin M response and cutaneous basophilic sensitivity decreased as a result of cold stress, and significantly increased by using NG (P<0. 05). The concentration of aspartae amino transferase and lactate dehydrogenase enzymes increased as a result of cold stress and addition of 20 mg NG/kg diet significantly decreased the mentioned enzymes concentration (P<0. 05). The lipid peroxidation index improved near meaningfully as a result of dietary NG (P= 0. 06). In general, the results of this study showed that using 20 mg NG/kg diet in cold stress condition led to improvement in immune and enzymatic responses of broiler chickens.

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    APA: Copy

    NEMATI, M.H., MOUSAVI, S.S., & VARMAGHANI, S.A.. (2020). Immune response and enzymatic activities of broiler chicks under cold stress to nitroglycerin. ANIMAL SCIENCES JOURNAL (PAJOUHESH & SAZANDEGI), 33(128 ), 205-216. SID. https://sid.ir/paper/385234/en

    Vancouver: Copy

    NEMATI M.H., MOUSAVI S.S., VARMAGHANI S.A.. Immune response and enzymatic activities of broiler chicks under cold stress to nitroglycerin. ANIMAL SCIENCES JOURNAL (PAJOUHESH & SAZANDEGI)[Internet]. 2020;33(128 ):205-216. Available from: https://sid.ir/paper/385234/en

    IEEE: Copy

    M.H. NEMATI, S.S. MOUSAVI, and S.A. VARMAGHANI, “Immune response and enzymatic activities of broiler chicks under cold stress to nitroglycerin,” ANIMAL SCIENCES JOURNAL (PAJOUHESH & SAZANDEGI), vol. 33, no. 128 , pp. 205–216, 2020, [Online]. Available: https://sid.ir/paper/385234/en

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