EFFICACY OF INACTIVATED H9N2 AVIAN INFLUENZA VACCINE AGAINST NON-HIGHLY PATHOGENIC A/CHICKEN/IRAN/ZMT-173/1999 INFECTION

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VASFI MARANDI M.; BOZORG MEHRIFARD M.H.; HASHEMZADEH M.

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Paper Information

Journal: ARCHIVES OF RAZI INSTITUTE Year:2002 | Volume:- | Issue:53 Page(s): 23-32

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Title

EFFICACY OF INACTIVATED H9N2 AVIAN INFLUENZA VACCINE AGAINST NON-HIGHLY PATHOGENIC A/CHICKEN/IRAN/ZMT-173/1999 INFECTION

Author(s)

VASFI MARANDI M. | BOZORG MEHRIFARD M.H. | HASHEMZADEH M. | Issue Writer Certificate

Keywords

AVIAN INFLUENZA

OIL-EMULSION VACCINE

VACCINATION

BROILER

LAYER

Abstract

An experimental AVIAN INFLUENZA (AI) OIL-EMULSION VACCINE was formulated with a ratio of 4 parts oil adjuvant ISA-70 and 1 part formalin inactivated A/Chickne/Iran/ZMT-101(101)/98(H9N2) antigen. Thirty 2-week-old Aryan BROILERs and thirty 2-week-old white Hy-line pullets were vaccinated subcutaneously. The latter was delivered a booster 10 weeks after primary VACCINATION. All vaccinated and control birds were bled for hemagglutination-inhibition (HI) test at least one week intervals. Half of the birds were challenged via intranasal and intravenous routes with a h9N2 strain at 8 and 27 weeks of age in BROILER and LAYER birds, respectively. High HI titers were observed in both vaccinated and unvaccinated birds, when examined at 2 weeks post-challenge (PC). Viral isolation or shedding from tracheal and cloacal swaps of both vaccinated BROILER and LAYER was decreased at 2 weeks PC, as compared with unvaccinated control birds. All control birds became morbid, and egg production decreased on day 3 PC. The results suggested that the inactivated oil-emulsion H9N2 AI vaccine may be protects both chickens against viral shedding and egg drop in filed conditions.

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APA: Copy

VASFI MARANDI, M., BOZORG MEHRIFARD, M.H., & HASHEMZADEH, M.. (2002). EFFICACY OF INACTIVATED H9N2 AVIAN INFLUENZA VACCINE AGAINST NON-HIGHLY PATHOGENIC A/CHICKEN/IRAN/ZMT-173/1999 INFECTION. ARCHIVES OF RAZI INSTITUTE, -(53), 23-32. SID. https://sid.ir/paper/528674/en

Vancouver: Copy

VASFI MARANDI M., BOZORG MEHRIFARD M.H., HASHEMZADEH M.. EFFICACY OF INACTIVATED H9N2 AVIAN INFLUENZA VACCINE AGAINST NON-HIGHLY PATHOGENIC A/CHICKEN/IRAN/ZMT-173/1999 INFECTION. ARCHIVES OF RAZI INSTITUTE[Internet]. 2002;-(53):23-32. Available from: https://sid.ir/paper/528674/en

IEEE: Copy

M. VASFI MARANDI, M.H. BOZORG MEHRIFARD, and M. HASHEMZADEH, “EFFICACY OF INACTIVATED H9N2 AVIAN INFLUENZA VACCINE AGAINST NON-HIGHLY PATHOGENIC A/CHICKEN/IRAN/ZMT-173/1999 INFECTION,” ARCHIVES OF RAZI INSTITUTE, vol. -, no. 53, pp. 23–32, 2002, [Online]. Available: https://sid.ir/paper/528674/en

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