EVALUATION THE EFFICACY OF ANTHRAX VACCINE AGAINST CHALLENGE WITH A HIGHLY VIRULENT STRAIN OF BACILLUS ANTHRACIS ISOLATED FROM SOIL IN SHEEP, GOATS AND GUINEA PIGS IN IRAN

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MOAZENI JOULA GH.R.; JABARI A.R.

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Journal: ARCHIVES OF RAZI INSTITUTE Year:2005 | Volume:- | Issue:60 Page(s): 21-31

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Title

EVALUATION THE EFFICACY OF ANTHRAX VACCINE AGAINST CHALLENGE WITH A HIGHLY VIRULENT STRAIN OF BACILLUS ANTHRACIS ISOLATED FROM SOIL IN SHEEP, GOATS AND GUINEA PIGS IN IRAN

Author(s)

MOAZENI JOULA GH.R. | JABARI A.R. | Issue Writer Certificate

Keywords

EFFICACY

ANTHRAX VACCINE

CHALLENGE

SHEEP

GOAT

GUINEA PIG

Abstract

Protection of animals immunized against Bacillus anthracis is usually demonstrated by challenging with an appropriate dose of a strain of Bacillus anthracis that is lethal to unvaccinated animals inoculated at the same time. In this study the protective EFFICACY in ANTHRAX VACCINE (34F2 sterne strain spore) was evaluated in SHEEP, GOATs and GUINEA PIGs CHALLENGEd with subcutaneous inoculation of a highly virulent Bacillus anthracis spores recently isolated from soil in Iran. This strain has been shown that it is lethal for SHEEP, GOATs and GUINEA PIGs in very low dose. It was found that the vaccine provides highly protection (100%) after challenging the immunized animals against this strain in SHEEP, GOATs and GUINEA PIGs. So, indicates the superior protective EFFICACY of the vaccine. The authors recommend that this strain can be used instead of other strain which has been used previously for challenging the immunized animals, and also GUINEA PIG is a good substitution for evaluating ANTHRAX VACCINE.

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APA: Copy

MOAZENI JOULA, GH.R., & JABARI, A.R.. (2005). EVALUATION THE EFFICACY OF ANTHRAX VACCINE AGAINST CHALLENGE WITH A HIGHLY VIRULENT STRAIN OF BACILLUS ANTHRACIS ISOLATED FROM SOIL IN SHEEP, GOATS AND GUINEA PIGS IN IRAN. ARCHIVES OF RAZI INSTITUTE, -(60), 21-31. SID. https://sid.ir/paper/539535/en

Vancouver: Copy

MOAZENI JOULA GH.R., JABARI A.R.. EVALUATION THE EFFICACY OF ANTHRAX VACCINE AGAINST CHALLENGE WITH A HIGHLY VIRULENT STRAIN OF BACILLUS ANTHRACIS ISOLATED FROM SOIL IN SHEEP, GOATS AND GUINEA PIGS IN IRAN. ARCHIVES OF RAZI INSTITUTE[Internet]. 2005;-(60):21-31. Available from: https://sid.ir/paper/539535/en

IEEE: Copy

GH.R. MOAZENI JOULA, and A.R. JABARI, “EVALUATION THE EFFICACY OF ANTHRAX VACCINE AGAINST CHALLENGE WITH A HIGHLY VIRULENT STRAIN OF BACILLUS ANTHRACIS ISOLATED FROM SOIL IN SHEEP, GOATS AND GUINEA PIGS IN IRAN,” ARCHIVES OF RAZI INSTITUTE, vol. -, no. 60, pp. 21–31, 2005, [Online]. Available: https://sid.ir/paper/539535/en

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