Evaluation of Ashitex and Imion on recovery of clinical symptoms, stress hormones and Interleukin 2 gene expression in Foot and Mouth Disease in cattle

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Poorkhalily M.; CHAMANI M.; SEIDAVI A.; SADEGHI A.

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Journal: JOURNAL OF RUMINANT RESEARCH Year:2020 | Volume:8 | Issue:2 Page(s): 23-38

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Information Journal Paper

Title

Evaluation of Ashitex and Imion on recovery of clinical symptoms, stress hormones and Interleukin 2 gene expression in Foot and Mouth Disease in cattle

Author(s)

Poorkhalily M. | CHAMANI M. | SEIDAVI A. | SADEGHI A. | Issue Writer Certificate

Keywords

Corticosterone

Cortisol

Foot and mouth disease

Immunoglobulin G

Interleukin

Abstract

Background and objective: Foot and mouth disease is a highly contagious disease of animal that is one of the major barriers to the provision of livestock health and livestock products. This experiment was conducted to investigate the effects of herbal medicines Ashitex and Imion on improving complications of Foot and mouth disease, decreasing stress hormones and increasing immune response in sick cows. Materials and methods: In this study, Ashitex and Imion, were orally sprayed to investigate their effects on improving the complications of Foot and mouth disease., reducing stress hormones and enhancing the immune response in cows with Foot and mouth disease. Ashitex is a blend of Turmeric, Myrrh, Mazoo and Liquorice, and Imion drug is based on Purple Coneflower. The experiment was performed on 75 cows with Foot and mouth disease. To obtain fully practical field results consistent with the cattle storage conditions, no changes were made to the storage conditions, such as feeding, light, temperature and other conditions, and only the cows were blocked and distributed in the prepared boxes. Treatments consisted of: 1-vinegar (control), 2-Ashitex, 3-Ashitex and Imion, 4-Vinegar and Imion, and 5-Vinegar and Ashitex. All treatments were applied for ten days. Ashitex was sprayed 20 ml twice daily. Imion was also given orally to the animal twice daily, 100 ml each time. At the beginning and end of the treatment period, blood samples were taken from the jugular vein of the cows to examine Interleukin II gene expression, immune responses, and changes in Cortisol and Corticosterone hormones. Findings: The second treatment (Ashitex) had the best performance on the appearance and general health of cows with Foot and mouth disease. The use of herbal medicine Ashitex improved the appearance and clinical conditions, as well as decreased stress hormones and increased expression of the gene effective in inflammation of cows with Foot and mouth disease. Imion also increased the production of Immunoglobulin G in cows with previously vaccinated Foot and mouth disease and increased the immune response. Conclusion: According to the results, the use of these two herbal medicines due to their combined effect and faster return to normal status and production cycle than other treatments is recommended to treat Foot and mouth disease.

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APA: Copy

Poorkhalily, M., CHAMANI, M., SEIDAVI, A., & SADEGHI, A.. (2020). Evaluation of Ashitex and Imion on recovery of clinical symptoms, stress hormones and Interleukin 2 gene expression in Foot and Mouth Disease in cattle. JOURNAL OF RUMINANT RESEARCH, 8(2 ), 23-38. SID. https://sid.ir/paper/963637/en

Vancouver: Copy

Poorkhalily M., CHAMANI M., SEIDAVI A., SADEGHI A.. Evaluation of Ashitex and Imion on recovery of clinical symptoms, stress hormones and Interleukin 2 gene expression in Foot and Mouth Disease in cattle. JOURNAL OF RUMINANT RESEARCH[Internet]. 2020;8(2 ):23-38. Available from: https://sid.ir/paper/963637/en

IEEE: Copy

M. Poorkhalily, M. CHAMANI, A. SEIDAVI, and A. SADEGHI, “Evaluation of Ashitex and Imion on recovery of clinical symptoms, stress hormones and Interleukin 2 gene expression in Foot and Mouth Disease in cattle,” JOURNAL OF RUMINANT RESEARCH, vol. 8, no. 2 , pp. 23–38, 2020, [Online]. Available: https://sid.ir/paper/963637/en

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