Introduction: Metabolic Triad is one of the risk factors of cardiovascular disease s (CVDs) which has an effective, determinant effect on these diseases. Hypertriglyceridemia and abdominal obesity (waist circumference) are among CVDs risk factors and the increase of these factors can predict the occurrence of TM. This project was aimed to investigate the relation of high phenotype triglycerid and waist circumference with CVD risk factors.Material and Methods: In a descriptive cross-sectional study, carried out in the year 2005, in Isfahan, 6123 men were selected based on the results of IHHP's phase I by random-cluster sampling method. Their blood sugar and blood lipids measured by blood sampling. Also, their blood pressure, waist circumference, height and weight measured. They were divided into 4 groups based on their tryglycerid and waist circumference: TgHWH group (TG2³165mg/dl, waist circumference ³102cm), TgHWL group (TG2³165mg/dl, waist circumference <102cm), TgLWL group (TG<165mg/dl, waist circumference<102cm) and TgLWH group (TG<165mg/dl, waist circumference £102cm). Data was analyzed by SPSS software. The variables of these four groups studied by variance test. Regression logestic test, used to determine the prevalence of risk factors. Results: The prevalence of risk factors in TgHWH group was higher than other groups and in TgLWL group lower than others. Also, it differed significantly these groups. The prevalence of TgHWH in the studied population recorded as 20.8%. Cholesterol, triglyceride, LDL cholesterol, Body mass index, and Blood Pressure in this group were higher and the mean HDL, was lower than others.Conclusion: In large population, it is impossible or non-economiccal and time consuming to evaluate all risk factors, in order to predict other CVD risk factors and to determine high risk people. However, according to the high prevalence of risk factors in people with TghWh, this phenotype can be used as a simple tool for evaluation in larger population.