In this research, Sesame (Sesamum indicum L var.shevin) seed germination characteristics under drought stress conditions influenced by different seed priming treatments were investigated. In two separate experiments, germination responses to different temperatures (1, 5, 10, 15, 20, 25, 30, 35 and 40 ° C) and also different drought stresses (water potentials of -9, -11, -13 and -15 bar) were considered. Based on the results, 25 ° C was determined as optimum germination temperature. The -11 bar water potential was also determined as drought stress. Hydropriming and osmopriming of the seeds were performed at three temperatures of 20, 25 and 30 ° C. The duration of priming was determined based on the priming temperature and type. Calcium chloride osmopriming treatment was performed in three concentrations of 1, 2 and 3 mM. The seeds were primed using potassium nitrate in three concentrations of 0.1, 0.2 and 0.3%. After priming using the mentioned treatments, the seeds were dried out to initial seed moisture content and then subjected to drought stress (-11 bar) during germination period to determine the best priming treatments. Priming treatments significantly improved seed germination characteristics under drought stress. Overall, The results of this experiment demonstrated that use of hydropriming for the seeds of sesame had the highest germination features. So this treatment can be presented as an appropriate treatment for this plant as it is cost-effective, safe and eco-friendly.