The aim of this study was to examine the relationship between perfectionism and mental health in a sample of students. A correlational analysis was performed to assess the kind of association existing among two types of perfectionism including positive perfectionism and negative perfectionism with mental health subscales including psychological well-being and psychological distress. One hundred and eighty five students (92 girls, 85 boys, 8 unknown) were included in this study. All participants were asked to complete the Farsi version of the Positive and Negative Perfectionism Scale (FPANPS) and Mental Health Inventory (MHI-28). Analysis of the data involved both descriptive and inferential statistics including means, standard deviations, analysis of variance, pearson's correlation coefficient, and regression analyses. The results revealed that positive perfectionism was positively associated with psychological well-being and negatively associated with psychological distress. The results also revealed that negative perfectionism was negatively associated with psychological well-being and positively associated with psychological distress. Positive perfectionism is supposed in to influence levels of mental health through enhancement of self-esteem and self-confidence and characteristics such as realistic thinking, acceptance of personal limitations, flexibility, and satisfaction from personal performance. Conversly, negative perfectionism is supposed to decrease levels of mental health through reducing self-esteem and self-confidence, as well as characteristics such as unrealistic thinking, unacceptance of personal limitations, inflexibility, and dissatisfaction from personal performance.