At present experiment the effects of coriander (Coriandrum sativum) seed powder on performance, humoral immunity, intestine morphology, litter quality, and footpad grade of broilers was studied. Four hundred male broiler chicks (Ross-308) were used in a completely randomized design with five treatments and four replicates at the age of 42 days. The experimental diets included: basal diet (negative control), basal diet + Lincomycin at 0.5% per kg diet (positive control), and basal diets containing 1, 2 and 3% coriander seed powder. There was no significant difference among the birds´ growth performance traits during 22-42 d of age, and also during the whole period of the experiment (1-42 days). Also, there was no difference among the birds´ livability and production efficiency index during 1-42 days of age (P>0.05). The birds fed with different levels of coriander had higher villus height (P<0.05). Coriander had no effect on moisture or pH of broilers´ litter, however, the inclusion of coriander in the broilers diet increased score 0 and score 1 parallel to a decrease in score 4 litter (P<0.05). Inclusion of coriander at the levels of 2% or 3% decreased the inci-dence of footpad dermatitis at score 2 or score 3 on d 42. Thus, using coriander seed powder at the levels of 1%, 2%, or 3% during 1 to 42 days of age improved renal biomarkers, villus height, litter quality, and foot-pad grade of broiler chickens.