Background and aim: Skin REJUVENATION is in demand. In recent years, mono- and bipolar radiofrequency (RF) have been reckoned as treatment of choice for this purpose. The studies on RF have shown the remodeling of collagen fibers and consequently improvement of skin texture although risks and side effects may exist.Methods: Forty-eight patients requesting skin REJUVENATION were treated by RF after obtaining written consent from them. The diagnosis had been made solely on the basis of examination and observation. The photography was performed in all patients pre- and post-treatment. The pictures were evaluated by a dermatologist unaware of the sequence of photos.Results: the wrinkles improved in 26 (54%) patients. The response was better with increasing age. Transient pain and erythema were reported by all patients.Conclusion: Radiofrequency is an appropriate treatment for reducing the number and the depth of wrinkles and needs comprehensive education. At least, 4 treatment sessions with 2-week intervals are required for effectiveness.

Introduction: Intense pulsed light (IPL) has long been used for skin REJUVENATION.Photo REJUVENATION with red light (with or without photo sensitizer) is a newer noninvasive way for this purpose; but, until now few comparative studies between these modalities have been performed. The aim of this study was comparing efficacy, adverse effects, and compliance of intense pulsed light REJUVENATION and red light photo REJUVENATION in a homogeneous group of women.Methods: In this clinical trial, ten female volunteers with Fitzpatrick skin type I, II, and III were enrolled. Patients underwent 6 sessions of IPL REJUVENATION at 4-week intervals on one side, and 30 photo REJUVENATION session (2 times a week) with red light on the other side of their face. Improvement of the skin texture and reduction in the wrinkles were determined in two ways. Firstly, by comparing the photographs, and secondly, by measuring the skin elasticity with Reviscometer MPA 9 system, before and after the procedure.Results: Both treatments were associated with improvement in the skin texture and wrinkle depth, but red light was more effective on the nasolabial fold and IPL was more effective on the fine wrinkles.Conclusions: Red light photo REJUVENATION without the use of photosensitizer can be a new, effective and safe procedure for REJUVENATION.