Background and Aim: The rapid and increasing growth of cancer disease in developed and developing countries and its multi-factorial and destructive personal, social and economic consequences have drawn this disease as a deliberate problem that threatens people's mental health, drawing special attention from specialists and researchers in the health field. . theaim of this research is to analyze the relationship between deficits in "executive function" and "processing speed" with "PTSD symptoms" in cancer patients, by examining the mediating role of fatigue and attention bias. Materials and Methods: This research was conducted by the path analysis-correlation method. Its statistical universe was all patients with gastrointestinal cancers (esophagus, stomach, colon, liver, and pancreas) referring to Tehran hospitals and medical centers (Iran) in the first six months of 2022. The statistical sample of this research was 158 men and women referring to two referal hospitals, who were selected for convenience sampling and participated in this research after obtaining informed consent. The research has used the post-traumatic stress disorder checklist (PCL-5), the Barkley Deficit in Executive Functioning Scale (BDEFS), Cancer Fatigue Scale (CFS), the Attention to Positive and Negative Information Scale (APNIS), and the Wechsler Adult Intelligence Scale (WAIS). The research data was tested using structural equation modeling method (path analysis),SPSS version 21 statistical software and Lisrel software were used to analyze the data. Results: According to the results of the path analysis, the direct path of the "executive function" ( β=-0. 249, T=-3. 328), the direct path of the "cancer fatigue (CRF)" (β=0. 31, T=64. 979), and the direct path of "positive attention bias"(β=-0. 341, T=-4. 648), " to the "PTSD symptom" is significant. However, the direct path of the "processing speed"(β=-0. 024, T=-0. 501) and the direct path of "negative attention bias" (β=-0. 104, T=-1. 774) to the "PTSD symptom" are not significant. The direct path of "executive function" to "cancer fatigue" (β=0. 623, T=10. 081) is significant, but, the direct path of the "processing speed" to "cancer fatigue" (β=0. 119, T=1. 932), direct path of "processing speed" to "positive attention bias" (β =-0. 008, T=-0. 132) and direct path of "executive function" to (β=-0. 367, T=-4. 782) to "negative attention bias" is insignificant. Moreover, according to the results, the indirect effect of the "executive functions" on the "PTSD symptoms" through "positive attention bias" is significant (b=0. 077, P<0. 05),but, the indirect effect of the "executive functions" on the "PTSD symptoms" through "negative attention bias" is not significant (b=0. 013, P>0. 05). The indirect effect of the "processing speed" to the "PTSD symptoms" through " cancer fatigue"(b=0. 066, P>0. 05), the indirect effect of the "processing speed" to the "PTSD symptoms" through "positive attention bias"(b=0. 005, P>0. 05), and the indirect effect of the "processing speed" to the "PTSD symptoms" through "negative attention bias" is not significant (b=-0. 001, p>0. 05). Conclusion: According to the existing research evidence, people show different reactions after being diagnosed with cancer, and during the treatment process, as a traumatic event. Considering the research results, it can be concluded that the experience of cancer-related stress disorder is influenced by cancer fatigue (CRF), information processing speed, and positive and negative attention bias. These results can be the basis for designing an intervention program to reduce symptoms of post-traumatic stress disorder (PTSD) in people with cancer, especially gastrointestinal cancers

Medical laboratories have significant role in diagnosis, management and follow up of the patients. Occasionally, some results are “, critical”, , meaning that urgent/emergent intervention is required in order to prevent major morbidities or mortality. During the last 40 years, significant attention has been paid to these results by laboratory specialists or clinicians. Rapid communication and reporting of critical results to management team has been emphasized and been considered as a requirement by some regulators. While rapid reporting of critical values has been accepted universally, the details of confirmation and rout of reporting has not been standardized. Herein, we present a brief review of various aspects of critical value results, such as how to diagnose, confirm and report them and describe theses process in our country and through the world in order to reach a rather harmonized protocol capable of being established based on regional conditions.

Debrunner and Flor Theorem can be extended to arbitrary θ-monotone operators. This generalization provides some tools for further analysis of the θ-monotone operators, which allows us for establishing some key facts related to domains and ranges of θ-maximal monotone operators.