PREPARATION OF TRANSDERMAL DELIVERY AND EFFECT OF MEMBRANE TYPE FOR SCOPOLAMINE DRUG

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ARABI HASAN; HASHEMI S.A.; AJDARI N.

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Iranian Polymer Journal Year:2002 | Volume:11 | Issue:4 (40) Page(s): 245-250

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Title

PREPARATION OF TRANSDERMAL DELIVERY AND EFFECT OF MEMBRANE TYPE FOR SCOPOLAMINE DRUG

Author(s)

ARABI HASAN | HASHEMI S.A. | AJDARI N. | Issue Writer Certificate

Keywords

TRANSDERMAL

DRUG

MEMBRANE

DELIVERY

SCOPOLAMINE

Abstract

The aim of this study was to clarify the performance of a MEMBRANE controlled reservoir system (MCRS) for SCOPOLAMINE hydrobromide (SH) under in vitro condition by determination of the role of MEMBRANE on SH rate control. In this method SH was incorporated into two polymers (polyisobutylene and polybutyl acrylate) and SH rate across ethylene-vinyl acetate copolymer (EVA) and ethyl cellulose (EC) MEMBRANEs were measured. The results obtained showed that in the EVA MEMBRANE, the permeability of SH across MEMBRANE increased with the increase of vinyl acetate percentage in copolymer. Microscopic studies of EVA MEMBRANE surface showed that the size of surface porosity increases with the increase of vinyl acetate percentage in the copolymer and due to this research, it showed DRUG increase of release rate. In the case of EC MEMBRANE, the results showed that the rate of release increases with the increase of porosity size of EC surface despite of having high molecular weight.

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APA: Copy

ARABI, HASAN, HASHEMI, S.A., & AJDARI, N.. (2002). PREPARATION OF TRANSDERMAL DELIVERY AND EFFECT OF MEMBRANE TYPE FOR SCOPOLAMINE DRUG. IRANIAN POLYMER JOURNAL (ENGLISH), 11(4 (40)), 245-250. SID. https://sid.ir/paper/533201/en

Vancouver: Copy

ARABI HASAN, HASHEMI S.A., AJDARI N.. PREPARATION OF TRANSDERMAL DELIVERY AND EFFECT OF MEMBRANE TYPE FOR SCOPOLAMINE DRUG. IRANIAN POLYMER JOURNAL (ENGLISH)[Internet]. 2002;11(4 (40)):245-250. Available from: https://sid.ir/paper/533201/en

IEEE: Copy

HASAN ARABI, S.A. HASHEMI, and N. AJDARI, “PREPARATION OF TRANSDERMAL DELIVERY AND EFFECT OF MEMBRANE TYPE FOR SCOPOLAMINE DRUG,” IRANIAN POLYMER JOURNAL (ENGLISH), vol. 11, no. 4 (40), pp. 245–250, 2002, [Online]. Available: https://sid.ir/paper/533201/en

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