Nepeta wuana H. J. Dong, C. L. Xiang & Z. Jamzad, (Lamiaceae), a new species found in Shanxi Province, China, is described and illustrated. The closest relative of the new species is the Chinese endemic N. sungpanensis C. Y. Wu but it clearly differs from it in the prolonged middle lobe of the lower corolla lip, as well as the much larger leaves, and sharper calyx lobes. Microfeatures of leaf epidermis, pollen grains, and nutlets of the new species are also explained.