The difference that exist between developed and developing countries, is technology particularly advanced technology. One of the advanced technologies is biotechnology that so interesting in recent years and achieved many successes in the domestic and international level. Biotechnology is one of the newest technologies which increase the agricultural productivity, accelerating recovery of diseases, eliminate environmental pollution and so on, to expand and its dissemination need to take measures that commercialization of technology is one of the most important ones. Today publishing paper and access to technical knowledge of new compounds in this field not hard, however, country has serious weaknesses in market entry and commercialization of biotech products. Technology pricing is one of the main steps in commercialization. Accordingly, this research sought to create a new framework to facilitate commercialization of technologies in the field of biotechnology through developing a model for the valuation and ranking of patents in this field. On this basis by deductive content analysis, effective criteria on technology pricing were derived from literature of this field, then were available to experts for allocating weight to each of criteria, weighting to the criteria was conducted by Fuzzy Logarithmic Least Squares Method (FLLSM), in the next stage by using the database at biotech development department of Presidential Deputy for Science and Technology and other biotech centers in the country, were extracted information of 54 registered patents in the quintuple areas of biotechnology (including marine biotechnology, ecology, chemistry, medicine, agriculture). Finally, patents of this applied areas were ranked by using Fuzzy Graph Theory and Matrix Approach (FGTMA). The results of this research revealed that market criteria are the most important effective parameters on technology value. Furthermore, attractive areas in the biotech sector are as follows: environment, agriculture, medicine, chemistry and sea.