Introduction: Iranian northern plain is surrounded by the Caspian Sea in North and part of the Alborz Mountains in South. These two geomorphologically distinct features have created unique climatic conditions. A plain lush with abundant rainfall is result of the proximity of these two distinct geographical regions. As a consequence, the Iranian Northern plain has been in use by human populations since the prehistoric times.The significance of coastal regions for human occupations has been documented all over the world. Abundance of food resources, access to the fresh water (rivers), and having clear landmarks have all made the coastal regions ideal geographical zones for human populations. In addition to that, proximity to the major water sources (big lakes, seas, and oceans) would regulate the climatic changes, and prohibits drastic alternations of the environment. Archaeological data have shown that coastal regions have also been used for human movements through prehistoric and historic times. Repeated exodus out of Africa is among such events.