BACKGROUND: By studying lipid and lipoprotein concentrations changes in the pregnant camels, methods can be found to reduce fertility problems and enhance reproduction efficiency in the species Bactrian camels.OBJECTIVES: This experiment was carried out to evaluate the effect of age, sex and pregnancy on serum lipid and lipoproteins in two humped Camels.METHODS: blood samples were collected from the jugular veins of 20 healthy camels according to their age (<10, 10-4 and >4 years), sex and pregnancy. Serum concentrations of total cholesterol (TC), triglyceride (TG), total lipid (TL), LDL-cholesterol, HDL-cholesterol and VLDL-cholesterol were evaluated.RESULTS: The concentrations of TG, HDL-cholesterol, LDL-cholesterol and VLDL-cholesterol in different age groups was significantly different (P<0.05). Age had a significant effect on the level of serum TG, HDL-cholesterol, LDL-cholesterol and VLDL-cholesterol of the camels, as in advanced ages, these parameters were lower except LDL-cholesterol. The concentration of LDL-cholesterol in immature camels was lower than adult ones. The concentration of TC was higher in male camels compared with females and this difference was significant (P<0.05). Tthe concentration of HDLcholesterol was higher in non-pregnant camels as compared with pregnant camels.CONCLUSIONS: Probably activation of sexual hormones during the puberty and hormonal interactions in the hypothalamus – pituitary - Gonadal axis (HPG) is the main reason for this phenomenon.