Abstract In recent years management of expenses in Azad universities has turned into a vital concern. The present study aims to examine investigating the effect of five factors including targeting activities, organizing manpower, mechanizing systems, controlling, observing and downsizing the university on reducing expenses in Islamic Azad Universities. The study is conducted in descriptive survey method and the population of the study was all 320 persons Islamic Azad university of Isfahan (Khorasgan). 175 people were chosen by Morgan Table through available sampling as the sample of the study. The instruments were questionnaires and the data was analyzed through Uni-variate t Test, Friedman Test, and Analysis Variance. The result revealed that all five factors in the study have significant effects on reducing expenses in the universities and controlling and observing had the highest effect whereas, organizing manpower had the least effect.