Context: In recent years, non-bone diseases have been shown associated with vitamin D deficiency, of which type 2 diabetes is a group of metabolic disorders caused by insulin deficiency. VitaminDdeficiency affects the metabolic function of the cells, including beta-pancreatic cells. Regarding the effectiveness of vitamin D to control type 2 diabetes, the present study aimed at reviewing the relationship between vitamin D, glucose homeostasis, and insulin resistance in type 2 diabetes. Evidence Acquisition: In this review, descriptive and analytic studies were analyzed using biochemical tests, questionnaires, and interviews. Using the keywords, such as vitamin D, type 2 diabetes, and insulin resistance, 11 articles, including descriptive-analytic, cross-sectional, case-control and interventional studies published from 1986 to 2018 were included. Results: The levels of 25-hydroxyvitamin D in diabetics, women, and obese people are lower than others, which can indicate the effect of vitaminDon glucose homeostasis. In addition, vitaminDaffects intracellular calcium, and, consequently insulin secretion. It can be said that vitamin D deficiency can make calcium unable to regulate insulin secretion. Conclusions: According to the studies, it can be concluded that vitamin D can be effective to prevent and control type 2 diabetes. Also, there is no association between vitamin D and insulin secreted by food and hemoglobin A1c.