One of the most important factors caused to reduce agricultural production in arid and semi-arid areas is water shortage during growth stage of plants. Thus in order to improve grain yield it is involved to assign a proper management method, which among them, it can be referred to the method of selecting the optimum density and proper system of irrigation. Through the arid and semi-arid region like Khuzestan province where its agriculture is critically based on water existence and irrigation, in order to optimize water usage and to maximize grain yield for per unit of water usage, it is necessary to converge all of agricultural operations.Therefore, to study effects of water shortage stress coincided during vegetative growth stages of corn and different levels of corn density on the corn grain yield, the yield components and economical water use efficiency, this research was conducted by applying method of split-plot based on randomized complete block design, with three replication in 2008 cropping season, at Shahid Salami field.In this experiment, water shortage stress due to cutting irrigation during vegetative growth stage were considered as a main factor at 4 levels that, including 1- cutting irrigation stress at 8 leaves-stage of growth, 2- cutting irrigation stress at 12 leaves-stage of growth, 3- cutting irrigation stress at teaseling stage, and 4- optimum irrigation; also corn density were considered as sub-factor in 3 levels, including 7.5, 8.5, 9.5 shrub per square meter. the obtained results indicated that effects of water shortage stress and different levels of corn density on the corn grain yield, the yield components, biological yields and economical water use efficiency significant.Stresses resulted from Cutting irrigation at teaseling stage and increasing the corn density under dominant condition of the experiment led to reduce the corn grain yield, the yield components and economical water use efficiency, compared to those in other vegetative growth stages.