The protection of justice and citizens especially while collaborating with criminal justice system staff on the one hand and differential criminal policy affected by the protective victimological findings, on the other hand, demands providing security to victims in proper ways. Also it is essential to provide the security for witnesses, who are involved in the process of discovering the truth are subject of risks and threats by the offenders organized, transnational, collective and vastness the crime of human trafficking requires that victims of trafficking, as a self-witness, could attend the court and testify for themselves and other victims. On the other hand, perpetrators and the other persons involved in committing human trafficking are very power full and somehow supported by high-rank members of the government. Thus, protecting the victims and witnesses of human trafficking and taking measures such as using pseudonym, not disclosing the identity of witnesses and victims to the public and mass media, testifying via video-conference, medical and psychologically equipped accommodating victims and witnesses during their court attendance, testifying at the enclosed doors and using reconstructed or fake pictures to prevent threatening and revenging and remove the incoming obstacles in the process of criminal justice especially in testifying are essential. Taking these security measures and other forms of protective measures about victims and under-age 18 witnesses must be considered seriously and accorded with their vulnerable state as much as possible. This article explores the protective approaches of the United Nations, Iran and Islam in providing the security for0 victims and witnesses of the crime of human trafficking.