We study the set of all determinants of adjacency matrices of graphs with a given number of vertices. Using Brendan McKay's data base of small graphs, determinants of graphs with at most 9 vertices are computed so that the number of non-isomorphic graphs with given vertices whose deter- minants are all equal to a number is exhibited in a table. Using an idea of M. Newman, it is proved that ifG is a graph with n vertices, m edges and { d1, …, dn} is the set of vertex degrees of G, then gcd (2m, d2) divides the determinant of the adjacency matrix of G, where d=gcd (d1, …, dn). Possible determinants of adjacency matrices of graphs with exactly two cycles are obtained.