Nowadays, acceptable banking service is impossible without e-banking. Recently, several crimes have been executed in the fields of e-banking, which the numbers of these kinds of crimes are increasing rapidly, which have caused customers damages. Subsequently, according to the mentioned issues, the necessity of presenting a comprehensive model in the field of information security in banks has become more important. Also, the old idea, which says the security will only achieve with the help of instruments and technology is not more acceptable. The purpose of this paper is to present a desirable quantitative model for information security in e-banking industry. The current research method is applicable from the purpose aspect and is mixed from the execution aspect. The statistical society in the qualitative study is composed of experts in the field of security and e-banking. In the qualitative part, the statistical society includes 18 experts and in the quantitative part, the statistical society includes 123 experimental experts. The analysis of the data is performed in the two separated parts in this paper. the first part is about qualitative statistics of research data. While, the second part is about inferential statistics of the research. The SPSS and PLS software are used to study in the research data. The study has shown that the seven parameters are mostly effective parameters on the e-banking security which are: OTP, ISOs, culture building, comprehensive education, infrastructures improvement, up to date software, and utilization of experts.