Ernest Renan, French scientist and orientalist, by presenting one of his most controversial speeches, by the title of Islam and science, in Sorbonne University on March 23th 1883 and then publishing it in Journal des Debats, started a series of intellectual discussions and penal disputes in Islamic and western world. Renan speech shortly after its publishing translated into German, English and then Arabic, Turkish, Urdu and Persian. Islamic thinkers from Sayed Jamal Al-Din Asad Abadi who resided in Paris at the time, to others such as Namegh kamal, Rashid Reza, Abd al-Razagh, Ata’Allah Bayazidov, Mohammad Hami Allah, Jalal Noori and ets…in Paris, Egypt, Ottoman, Ghazan, India and Pakistan wrote several rejections on Renan claims. These rejections themselves then turned into one of the main researching resources to know Sayed Jamal al-Din Asad Abadi’s intellectual personality. However in Iran this problem is still unknown. It is impossible to find any other rejections against Reanan in Persian resources except one which belongs, to Sayed Jamal al-Din Asad Abadi, yet most of mentioned rejections from Ottoman’s era has been translated or compiled into Turkish language. In this article for the first time the most important rejections of Islamic world thinkers have been recognized and reviewed. Most of the information used in this article belongs to Ottoman or modern Turkis resources.