The concept of “The Transcendental” is the term Plotinus ascribes for “the One” to make it transcend all diversities, limitations, and personifications.This transcendency makes a great distance between the source of the existence, “the One”, and the other creatures; and accordingly this distance would bring into a challenge the most basic tenets of mysticism, i.e. “relation” and “love”. Plotinus mystic thought is basically philosophical, and in his mystical approach toward philosophy, there is no trace of excitement, ardor, and zeal that are the characteristics of Eastern poetic mysticism. Though Plotinus’s ideas have influenced the eastern mysticism and philosophy, his mysticism is originally based on Greek philosophical thoughts. The notion of “the transcendental” is an adoption from the idea of “good nature” in Plato’s and Plotinus’s thoughts. Adopting this concept and detaching “the One” from all humane characteristics such as thought, love, will, blessing, and mercy, would bring into being the concept of a God which is alien, extremely far, and silent. This article is to study the concept of the transcendent to investigate the source of existence in Plotinus’ thought, and the way it is used in transcending “the One”. Following the transcendence of God to “the One”, the notion of “creation” would also turn into “grace” so that there will be no need to God’s determination and awareness.