The research aiming to analyze, describe water interactions between Iran, Iraq, Afghanistan from 2001 to 2010. International Security process depends on variety of Independent Variables. Water is one of those Strategic parameters. Indeed, Water can play as a fundamental source of peace, security & conflict among UN member states foreign policy. Nonetheless, U.S. is Iran's neighbor after Mexico and Canada inside occupied Afghanistan and Iraq. Is it a threat? Water scarcity in a region can generate variety of insecurities. Global threads like dust storms, drug, HIV Aids, terrorism, pollution, poverty and environmental crisis, can travel easily around the world and moving across national borders. In opposition, human security paradigm, introduce variety of different type of security, like economic, political, social, health, personal, environmental security. Human security has not any link with weapon. "Human security entails basic material needs, human dignity, Human security describes a condition of existence in which basic material needs are met and in which human dignity, including meaningful participation in the life of the community, can be met". Promoting basin wide human security, not only, for Iran's people, but also for neighbors, would bring peace, security and stability.