Iranian architecture, established in the 8th century with its roots in the forms and buildings of Seljuk, was expanded and exalted during the Timurid period. In the reign of Shahrokh, very valuable historical monuments were built. Sultan Shahrokh Teymouri together with his wife gave rise to a kind of cultural renaissance through supporting art and attracting artists, architects, philosophers, and poets to their court. The existence of Imam Reza (A.S.)’s Holly Shrine in Mashhad and its proximity to Harat caused this city to draw bourgeoning attention during this period. In this regard a number of historical monuments such as Goharshad Mosque, Madrasa-i-Dodar, Madrasa-i-Bala-sar, Dar al-Huffaz, and Dar al-Siadah were established in the south and west of Imam Reza (A.S.)’s Holly Shrine. Shah Mosque or the Mosque of the 72 Persons, located in the south-west of Goharshad Mosque and along the former Zanjir Bazaar, is one of the magnificent monuments of the Timurid period in Mashhad. In recent years, subsequent to discovering some tombstones under the dome, the primary assumption that this monument had been a tomb and had mistakenly been introduced as a mosque grew stronger. In accordance, several research papers confirming this monument as a tomb were also published. However, given the changes made to this monument in different periods, renaming the shrine a mosque is rather debatable. Today, there is no consensus over either the function and nature of this monument or its construction date, founder, constructor, etc. Thus, in this study, the author attempted to address such ambiguities by investigating the historical documents and the existing inscriptions on the monument.The results indicated that, this monument can be considered as one of those tomb-mosques with an amalgamation of the two functions.