Judaism, one of the great divine religions in the Holy Quran, has suffered some deviations (including economic deviations) throughout history. It is necessary to study the contexts, factors of deviation and influence of Jewish rule on human societies from the perspective of the Holy Quran. Using analytical-descriptive methods and open and closed coding based on Quranic verses and valid interpretive viewpoints, this article first discusses the most important economic corruptions (such as extreme greed and avarice, hoarding, financial betrayal, prohibited transactions, stinginess, money-grubbing, breaking financial contracts and the prevalence of usury) among the Jews. Then it analyzes and describes the three factors of beliefs, ethics and behavioral habits and finds the factors of economic deviation of the Jews. Therefore, firstly, the main factor is materialism, paying attention to worldly matters, lack of real faith, polytheism and false beliefs; and secondly, whims and fancies are the most basic moral factors that cause pride, selfishness, materialism, and financial deviation for the Jews; and thirdly, behavioral habits affected by the first two factors has led to involuntary habits (such as lying, cruelty, enmity) and thus economic deviations.