Summary: In this paper, in-operation mines of Azerbaijan-e-Gharbi Province, as a mineral-rich province of Iran, are ranked using multi criteria decision making methods. However, in this study, the analyses are done under the fuzzy environment to reduce the ambiguous and uncertainties. The results of this study show that, the iron and gold mines are the first priorities, chromic and manganese mineral types are the second priorities and the lead and zinc mines are the third priorities. Introduction: Mines and mining industries are an important way to reach the sustainable development and investing in these sectors creates the suitable economics value added. Therefore, prioritization of the mineral activities are helpful for persuasion of future investments. The main aim of this research is to rank the mining activities of the Azerbaijan-e-Gharbi Province in Iran with considering five main criteria including economic, cultural and social, environmental, technical and also political criteria. Methodology and Approaches: In this study, the main in-operation mines are considered. The technique for order of preference by similarity to ideal solution and also the analytical hierarchy process are used to prioritize the mining activities. To reduce the uncertainties, all calculations are done under the fuzzy environment. Results and Conclusions: Results of this study show that, the cultural, social and environmental criteria have the highest importance degree in comparison to the other criteria. The iron and gold mines are the first priorities, while the chromic and manganese mines and lead and zinc mines are respectively the second and third priorities. The quarry and gypsum mineral types, the barite, red and yellow soil, kaolin, fireclay and dolomite, salt and silica, sand, rubble, mica, limestone and ballast mines are respectively ranked also.