Background: Research suggests that diabetes mellitus (DM) has a negative impact on employment and workplace injury, but there is little data within the Canadian context. Objective: To determine if DM has an impact on various occupational health outcomes using the Canadian Community Health Survey (CCHS). Methods: CCHS data between 2001 and 2014 were used to assess the relationships between DM and various occupational health outcomes. The final sample size for the 14-year study period was 505 606, which represented 159 432 239 employed Canadians aged 15– 75 years during this period. Results: We found significant associations between people with diabetes and their type of occupation (business, finance, administration: 2009, p=0. 002; 2010, p=0. 002; trades, transportation, equipment: 2008, p=0. 025; 2011, p=0. 002; primary industry, processing, manufacturing, utility: 2013, p=0. 018), reasons for missing work (looking for work: 2001, p=0. 024; school or education: 2003, p=0. 04; family responsibilities: 2014, p=0. 015; other reasons: 2001, p<0. 001; 2003, p<0. 001; 2010, p=0. 015), the number of work days missed (2010, 3 days, p=0. 033; 4 days, p=0. 038; 11 days, p<0. 001; 24 days, p<0. 001), and workrelated injuries (traveling to and from work: 2014, p=0. 003; working at a job or business: 2009, p=0. 021; 2014, p=0. 001). Conclusion: DM is associated with various occupational health outcomes, including workrelated injury, work loss productivity, and occupation type. This allows stakeholders to assess the impact of DM on health outcomes in workplace.