In today’s interconnected and knowledge-driven global political economy, it is essential to establish the right balance between the national economies of non-industrialized countries and the international political economic system, which is dominated by industrial and developed countries. Underdeveloped countries need to consider intellectual property rights to achieve growth, attract investment, promote trade, raise standards, improve productivity, facilitate industrialization, enhance competitiveness, and achieve comprehensive development. Unfortunately, in many cases, the challenges of achieving economic and social development in developing countries have been worsened by the rules and regulations established in international regimes. This is a dynamic process of power, order, and diplomacy. The main research question is “What impact do the actions of international institutions, such as the World Intellectual Property Organization (WIPO), in implementing a development-oriented approach to intellectual property rights, have on the economic performance of developing countries?” The initial response is: “The actions and initiatives of international institutions like WIPO in helping to improve the economic performance of developing countries have primarily been within the framework of a promotional and empowerment process aimed at cognitive transformation, legal adaptation, structural reconstruction, and significant changes in public culture. This is because, due to their dependency on the networked capitalist economic system, they have no alternative but to adapt, and coordinate.” The implementation of these institutional and social transformations in the political economy of developing countries, to regulate and stimulate innovation, industry, and artistic creativity, is fully justified, beneficial, and efficient. This provides a relative, general, and encouraging improvement for the growth and prosperity of these countries. However, expecting greater achievements depends on the considerations, interests, and strategic equations of powerful countries and companies. The reciprocal effects of empowering developing countries require strong economic capabilities and multi-level diplomacy involving emerging powers