Background: The comorbidity of generalized anxiety and major depressive disorders and the challenges of distress disorders led to developing a model such as emotion dysregulation. The present study sought to examine the emotion dysregulation model of distress symptoms in a community sample. Materials and Methods: 508 individuals recruited from a community sample using convenience-sampling method. Participants filled in the questionnaires assessing safety motivation and emotional intensity, emotion regulation strategies (attentional control, acceptance, decentering, and reappraisal), and distress symptoms (depression, generalized anxiety symptoms, worry, and rumination). The structural equation modeling was used to assess the fitness model. Results: The model yielded a good fitness, χ 2=64. 51, df=26, χ 2/df=2. 48, P<0. 001, CFI=0. 97, GFI=0. 97, PCFI=0. 56, RMSEA= 0. 05. The emotion dysregulation model of distress symptoms has an acceptable fitness. Conclusion: The mediating role of emotion regulation strategies in this model highlight the important effects of emotion regulation abilities in protecting individuals suffering from distress symptoms.