The present study was conducted by combining previous research with the aim of providing a comprehensive picture of the components of the role of spouses in the entrepreneurship ecosystem of women. The research methodology is qualitative with a meta-synthesis approach. Accordingly, after searching the databases, in the period of 1385 to 1399 for domestic researches and 2000 to 2020 for foreign researches, 124 related studies were evaluated and finally, after multiple screenings, 62 articles were selected. Using seven-step model of Sandelowski and Barroso, the findings of 62 previous studies related to the objectives of the study were reviewed, aggregated, combined and interpreted, and with the help of coding method, 22 codes, 4 concepts and 2 components were identified and validated through Kappa Cohen coefficient. Then, according to the Iranian society, the appropriateness and the importance and priority of the identified concepts were determined and evaluated using the Delphi method. As a consequence, according to the findings of the research, the concepts of spouses' role on women's entrepreneurship ecosystem based on Delphi method and the degree of importance are obstacle, supportive, intervening and encouraging, respectively. In addition, the role model of spouses in entrepreneurship ecosystem of women was presented and drawn. Finally, in line with the research results, practical suggestions that can provide valuable insights to managers and policymakers seeking to improve women's entrepreneurship and increase entrepreneurial behavior in society are presented. furthermore, practical suggestions for the actors who play in the entrepreneurship ecosystem of women at the operational level are presented.