Intensity Modulated Radiation Therapy (IMRT) is one of the moderntechnologies of external radiotherapy, which underwent widespread clinicaladoption in medical centers. Modern radiotherapy makes use of new technologies in design, treatment, and delivery systems. However, despite theadvantages of IMRT compared to previous methods, radiotherapy errors are still an obstacle to achieving the desired dose distribution. In this paper, effective errors of the IMRT technique, together with the sensitivity ofdifferent quality assurance (QA) procedures in diagnosis are investigated andclassified. According to these studies, in addition to the importance of humanerrors in delivery and patient positioning, beam correction device errors areother most effective sources of delivery errors, responsible for 35% to 50% ofradiotherapy uncertainties. Thus, IMRT QA methods such as diode detectors, films, electronic portal images, log files, and artificial intelligence methodshave been used extensively to investigate the MLC leaf positioning errors. Moreover, uncertainties of treatment couch design and MLC modeling in TPSshould not be underestimated, since numerous studies have demonstrated thatvarious couch tops include non-negligible beam attenuation, ranging from 4%to 9% for a gantry angle of 0° . Whereas posterior oblique beams are often usedin the IMRT process. This article aims to highlight the importance ofrecognition and correction of radiotherapy uncertainties and reduce possibleaccidents during an IMRT process by precisely knowing various IMRT QAprocedures.