The goal of this study was evaluation of the relation between nasal fungal infection and nasal polyp. In this study 28 cases, 24 males (86%) and 4 females (14%), without any immunological disorder, diabetes mellius or history of radiation or chemotherapy, who were candidates for nasal polypectomy, were selected as the patient group. 28 cases, without any immunological disorders, diabetes mellitus, or history of radio or chemotherapy, we selected as the control group. Nasal polyps were studied for fungal granuloma, hyphae or charcot-liden crystals. Polyp and nasal secrations of both groups were cultured in methenomine silver for fungus. There was history of asthma in 3 (10.7%), sensitivity to aspirin and asthma in 1 (3.5%), history of allergy in 17(60.7%), and previous surgery for polyps in 13(46.4%) cases. Nasal obstruction was the first complaint in 20 persons (71.4%). Bilateral nasal polyp was seen in 27(96.4%) cases, Sinusitis of bilateral maxillary and ethmoid was seen in 20(71.4%). Involvement of other sinuses was as follows: sphenoid sinus in 13(46.4%), frontal sinus in 11(39.2%), and pansinusitis in 8(28.5%) cases. No thick mucinoid secretion was seen in the nasal cavity. Histopathologic results for all patients were inflammatory polyps with no charcot-liden crystal defects. Culture was negative for fungus in both groups.