Hormozgan Medical Journal
Year:2005 | Volume:8 | Issue:4|Papers Count:14

Introduction: Fat embolism syndrome refers to the presence of fat globules in lung parenchyma and/or peripheral blood circulation. The syndrome most often is seen in association with long bone or pelvis fractures and can lead to patients death. Considering prophylaxis the strongest argument has been about the efficacy of corticosteroids.Methods: This study was conducted to determine the efficacy of corticosteroids in prevention of fat embolism syndrome and arterial hypoxia in 91 patients with long bone fractures. Patients meeting the inclusion criteria were divided randomly to control and case groups and the case group received the drug. Results: In total, 2 cases of fat embolism syndrome were observed in the corticosteroid-treated group (5/2%) and 6 in the control (10/1%) (P=04). Arterial hypoxemia was observed in one of the corticosteroid-treated group (2/6%) and in 8 of the control (15.0%) (none of them severe) (p=0.07). The mean arterial oxygen pressure did not show any statistically significant difference (p=0.07).Conclusion: According to this data, methylprednisolone succinate, in the used dosage, is not effective in prevention of fat embolism -syndrome and arterial hypoxemia.

Introduction: Fetal loss and abortion are responsible for significant emotional distress for couples desiring children. Regarding the etiologic importance, this study has been carried out to determine the prevalence of Anti-Chlamydia trachomatis antibodies in normal women and women with abortion.Methods: In this descriptive study 120 women with definite diagnosis of abortion as patients and 150 matched women with at least one successful delivery and negative history of miscarriage as controls were studied. The sera of the patients and the controls were tested by ELlSA method for to determine Anti-Chlamydia trachomatis antibodies.Results: There was a significant difference between prevalence of anti-Chlamydia trachomatis antibodies in the patients and the controls (p<0.001).Conclusion: The results of this study suggest that Chlamydia trachomatis plays a significant role in abortion in this area. Further studies are needed to explore the role in abortion in this area. Further studies are needed to explore the role of Chlamydia trachomatis in abortion.

Introduction: lntraocular pressure (IOP) is determined by three factors: the rate of aqueous humor production by the ciliary's body, the resistances to aqueous out flow across the trabecular meshwork and the level of episcleral vessel pressure. IOP varies with a number of factors, including: age, sex, race, systemic disease and diurnal variation.The purpose of this study is measurement of IOP and CID ratio in normal population.Methods: 200 persons who accompanied the patients referring to Shahid Mohammadi clinic underwent total eye examination, measure of IOP and CID ratio. The obtained data was then subject to Chi-Square test and Pearson Correlation Coefficient analysis (p< 0.05).Results: In statistical result, IOP> 14 in the left eyes of persons with history of familial glaucoma was more than persons without familial glaucoma (p< 0.01). the same result was attained for the right eyes.Also CID ratio was higher in persons with glaucoma familial history (p< 0.01). There was a positive correlation between age and right eye IOP (r=0.37) and left eye lOP (r=0.41) also there was a positive correlation between age and CID ratio.Conclusion: Age has an important effect on increasing IOP and CID ratio in both eyes, no difference between myopic and non myopic persons in IOP & CID ratio, and there is not any effect of myopic on IOP and CID ratio.The study suggested familial history of glaucoma has an important effect on increasing IOP and CID ration in both eyes.

Introduction: Lupus nephritis is a systemic disease which affects different organs. The present study was designed to review lupus nephritis, in children its outcome and the related factors.Methods: We reviewed 48 children with lupus nephritis. Clinical and epidemiological features were studied. The patients' outcomes and related factors were analyzed. Patient and renal survival rate were calculated.Results: The patients were aged 3-11 years. All of the patients had proteinuria and hematuria at the time of presentation. The most common type of renal pathology was class IV lupus nephritis. In follow up, 29.2% and 25% of patients had chronic renal failure and hypertension respectively. The most significantly associated factor was the presence of hypertension at the time of presentation (p=0.03). Five year renal survival rate was 63.8%.Conclusion: Age, sex and renal pathology prevalence of children with lupus nephritis in present study is similar to other studies. Hypertension is a significant predictive factor, so it needs more attention for early treatment of hypertensive patient with lupus nephritis. Less favorite renal outcomes in the present study needs more investigation.

Introduction: Acne is a disorder of the pilosebaceous unit of the skin and can present as non inflammatory and or inflammatory lesions. Tretinoin has been used therapeutically for over three decades. It is best known for its comedolytic effects on acne. It also inhibits comedone rupture, thus decreasing inflammatory events. Tretinoin is available in 0.01% to 0.1% as cream, gel or lotion. The objective of this investigation was to evaluate the physicochemical stability of various dermatological preparations of tretinoin marketed in Iran. Methods: The in vitro release and penetration characteristics of tretinoin from different formulations (Stieva-A solution, Retin-A cream, Retin-A gel and three Iranian brands) were studied through a hydrophilic Dora pore diffusion barrier and membrane excised rat skin using Franz cell over a period of 5th.The amount of drug released from topical preparations were determined spectrophotometrically at Amax=352 nm. Furthermore, the physicochemical stability of each formulation including drug assay, content uniformity, viscosity, pH, cyclical temperature test and centrifugal separation test were investigated.Results: The obtained results showed that the formulations studied presented both good chemical and physical stabilities. The generated rank order for the drug release from different preparations using membrane was observed to be Stieva A solution> IR-tretinoin lotion> Retin A cream> Retin A gel> IR-tretinoin gel> IR-tretinoin cream. The in vitro penetration of tretinoin through excised rat skin showed that the cumulative percent of penetrated drug at the end of each experiment were 10.8%, 14.75% and 25.2% for IR-cream, IR-gel, Retin A cream and Retin A gel respectively.Conclusion: The in vitro release kinetics of tretinoin is affected by the kind of pharmaceutical dosage form. The release of drug from gel formulation obeyed higuchi's kinetics, whereas the kinetic of drug release from cream was first order model.

Introduction: Knowledge of curvature situation of teeth plays an important role in successful endodontics treatment. For a proper endodontic treatment, it is not only important to know the form of normal anatomy of teeth but one must also know its possible different form. The goal of this study was curvature study of the first maxillary molar human teeth.Methods: In this descriptive study curvature situation of the first maxillary molar teeth, of 105 human teeth with unknown age, gender and cause of extraction were investigated. They were collected so as to ensure molarity of the sample. When the samples were cleaned manually, they were put in a dish containing diluted sodium hypochlorite. An appropriate access cavity was prepared. 1% fuchsine was used for dyeing for 20 min. Dye permeation into the making it easier to identify the canal position.Three methods of study, by observation, by X-ray stereotypes and by crosssections were used in order to recognize the number and type of the canals, number of canal openings, number of apical foramens, bending direction in the root, the compatibility of root end and the schema of the bottom of the access cavity. The results are provided in special ID certificate according to the relevant codes.The cross-sections were more emphasized in studying the number and type of the canals, and the observation and X-ray methods were used for studying the bending of the canal. The schema of the foramen apical was studied by observation and cross-sections.Results: The results of the research were as follows. A curve was observed in 63.8% of the palatal roots, 48.6% of the distal roots and 80% of the mesial roots. Apical foramens matched the end surface of the apex root in 55.2% of the palatal roots. 54.3% of the distal roots and 46.7% of the mesial roots. Conclusion: The probability of existence curve in the mesiobuccal root in first maxillary molar is more than the other roots but match of apical foramen with the end surface of the apex root is less than the other roots.

Introduction: Finding the importance of safe water, developed countries, have solved many of their health problems. In Iran, as there are not enough regular available and railways and airways, buses are the main way for transportation. Pollution of drinking water in those buses is a serious way for spreading waterborne diseases. This survey has been conducted to assess the quality of drinking water of Bandar Abbas road ways buses. Methods: In this descriptive study, 38 samples were taken. MPN test was preformed with 3 tubes (method based on related standard), residual chlorine was measured by DPD kit, turbidity was tested by tubid meter and pH was measured by use of portable pH meter. Test results were presented as descriptive statistical data.Results: In all samples, residual chlorine was zero; pH was in range 7-7.5. Out of 6 MPN positive samples (probably microbial pollution) 2 cases were Volvo buses, 2 cases were Benz buses and 2 cases were related to water tank of bus terminal. 24 samples didn't meet turbidity standard (suitable level). Conclusion: The survey found there is no relationship between type of bus and drinking water pollution and possibly water pollution is due to secondary factors, such as ice pollution, water cooler tank and so on. In addition, secondary factors can be the cause for a high level of turbidity in some samples.

Introduction: It is widely believed that, if women want to have healthy pregnancies and infants they must use the prenatal care that is essential. This study investigated the obstacles to prenatal care in women referring to maternity hospitals in Kerman.Methods: This study is a descriptive study, which was carried out to study the view of 400 pregnant women toward obstacles to prenatal care. In this study a pre-designed questionnaire was used for data collection and descriptive statistics, ANOVA and Kruskal Wallis tests were used for data analysis. In this study obstacles were divided into three subscales of system barriers, provider barrier and patient's barriers.Results: This study showed that, in system barriers the highest percent (58.7%) belongs to the lack of transportation and other barriers were inappropriate place for providing prenatal care (4.31%) and long time waiting for receiving care (9.30%). In provider barriers the highest percent (2.7%) belongs to in adequate reach and follow up. The result also shows that in patient barrier the highest percent (35.1%) belongs to unwanted pregnancy. The result related to comparison barriers with some demographic variables showed some significant differences.Conclusion: Because prenatal care prevents problems during pregnancy and delivery so we have to reduce the obstacles that result from this study.

Introduction: Hospital managers make decisions based on the statistics and information obtained from Statistic and Medical Records Department (SMRD). Methods: This is a descriptive-analytical study which is to determine the knowledge and attitude of Hormozgan province hospital administrator regarding SMRD. 18 hospital administrators underwent study.Results: The among governmental hospital administrators, 23.1% had weak, 62.2% moderate and 7.7% good SMRD knowledge respectively. While SMRD knowledge of nongovernmental hospital administrators was 80% moderate and 20% good respectively.Conclusion: Hospital administrators must have adequate knowledge of all hospital departments including medical records department. The results of this investigation showed that Hormozgan hospital managers do not have adequate knowledge of medical records department functions which may lead to inefficient functioning of other departments and cause economic, social and political damages.

Introduction: Nurses constitute the largest and most important community in hospitals-the main centers providing health services which have a leading role in the health of society. Job satisfaction is one of the most effective factors on quality of health services provided by nurses. The present study aimed at assessing job satisfaction of nurses in Hormozgan University hospitals. Methods: In this cross-sectional descriptive study, 200 nurses working in Bandar Abbas hospital were randomly selected. Measuring instrument was a questionnaire to evaluate the job satisfaction and relevant affecting factors. SPSS was utilized to analyze the data.Results: The results indicate that 3.5% of nurses were completely satisfied 5.5% of them were satisfied, 34% were not satisfied and 27% of the nurses were completely dissatisfied. Also this study indicates that there is a significant relation between job satisfaction and age, marriage status, number of children, level of education, work experience, position, ward and monthly income (p<0.05). Conclusion: There are many factors that affect job satisfaction in nurses. It seems that health system managers should pay much more attention to nurses' problems to solve them.

Introduction: Follicular thyroid carcinoma (FTC) is the second most common malignant form of thyroid cancers. FTC is more common in women with a peak: incidence in the fifth and sixth decades of life. Invasion into blood vessels may lead to distant metastasis to bone, lung, liver or elsewhere. FTC rarely manifests itself as a distant metastatic lesion, especially as solitary metastasis.Case report: Here we present a 65 years old woman with nodular goiter with cytologic diagnosis of adenomatous goiter. In follow up, she presented with a skull mass which had an osteolytic appearance in parietal bone.Biopsy from skull mass, showed metastasis from FTC. This diagnosis was confirmed in histologic examination of the thyroidectomy specimen. Conclusion: Thus, in approaching thyroid nodules, the limitations of fine needle aspiration-cytology in differentiation of follicular lesions must be remembered. Also in patients with nodular goiter and evidence of metastasis, possibility of thyroid carcinomas as primary origin should be considered.