مجله دانشگاه علوم پزشکی اراک
سال:1392 | دوره:16 | شماره:5 (پیاپی 74) |تعداد مقالات:13

Background: Heat shock proteins (HSP) are from proteins family playing a crucial role in maintaining cellular hemostats and protecting cells in acute and chronic stressful conditions. The objective of this study is to investigate the alternation of heat shock proteins (HSP70) levels after Wingate and Strand tests in female students.Materials and Methods: In this semi-experimental study, 40 female students (20 athletic and 20 non-athletic) with the mean age of 22.3±3 and 23.2±2 years, height of 159.2±5 and 161.2±4 cm, and mean weight of 59.3±3 and 65.4±2 kg, respectively were selected randomly and underwent training protocols of Wingate and Strand tests with 3-day intervals. Five cc brachial vein blood samples were taken immediately before and after performing tests in order to analyze the data using repeated measures analysis method.Results: The findings showed a significant increase after aerobic Strand test in athletic and non-athletic females (P<0.01). However, after aerobic Wingate test, a significant increase was observed only in athletes' group (P>0.05). There was an insignificant reduction in the non-athletic group.Conclusion: The results showed that exercise duration is more important than exercise intensity in HSP70 production.

Background: There is priority for evaluation of micronutrients (vitamin A) in the world, especially in develpoing countries like Iran. Vitamin A has an essentiall role in growth, reproduction, and maintenace of epithelial cells. Vitamin A, especially retinoic acid, acts like a hormone for gene expression. Vitamin A is necessary for growth of bones and immune system. The role of vitamin A in reducing mortality rates of neonates is well recognized. The aim of research is to evaluate this micronutrient (vitamin A) and the rate of transportation from mother to fetus and its positive effects on birth weight.Materials and Methods: In this descriptive study, 90 pregnant mothers were selected from private and public hospitals in Arak. Data gathered through a questionnaire including general information concerning pregnant mothers and also their nutritional diet. The analysis of dietary intake was done by Nutritionist IV software. The measurements of serum and cord blood retinol samples were carried with reverse phase HPLC.Data analysis was done by Pearson correlation.Results: The results indicated a positive and significant correlation between cord blood retinol of mothers and birth weight of neonates (r=0.22) (P£0.05). There was not a significant correlation between serum retinol of the mothers and birth weight of the neonates. Also, there was no significant correlation between retinol intakes of the mothers and birth weight of the neonates.Conclusion: Improvement of the retinol status of mothers has an effective role in normal birth weight of neonates.

Background: Caesarean section is one of the most common gynecologic surgeries and nausea and vomiting after pain are the most common side effects of surgeries. Today, serotonin receptor antagonists are most widely used that are the most effective antiemetics and have less side effects compared with other drugs. Ondansetron is considered a typical serotonin antagonist.Materials and Methods: This randomized, double-blind clinical trial was done on 162 women undergoing cesarean section. Four mg intravenous ondansetron was administered to the first group and 8 mg oral ondansetron was given to the second group and the third group received placebo. Blood pressure and heart rate were measured before and immediately after performing spinal anesthesia every 5 minutes until 20 minutes. Post-operative nausea and vomiting and APGAR score were recorded after operation in recovery and 2, 4, and 6 hours after surgery.Results: There were no significant differences among the 3 groups according to age, gravidity, mean atrial pressure, and heart rate before and during surgery. Nausea and vomiting in oral and intravenous groups at recovery 2 and 4 hours after surgery were significantly less than placebo group (P<0.05), whereas there were no significant differences between oral and intravenous groups.Conclusion: It can be concluded that using oral ondansetron with the same antiemetic effect is more appropriate for women undergoing cesarean section with spinal anesthesia.