JOURNAL OF BABOL UNIVERSITY OF MEDICAL SCIENCES (JBUMS)
Year:2003 | Volume:5 | Issue:2 (18)|Papers Count:14

BACKGROUND AND OBJECTIVE: Mummify is a semisolid material which comes out from fissures of caves and contains hydrocarbons, oxygen, nitrogen and sulfur. This material has a specific position among people of Jiroft town as a healing agent of skin wounds. The objective of this study was to determine the local effect of mummify as a topical application on skin wound healing and its comparison with phenytoin cream. METHODS: This experimental study was performed on three groups of male rats. After anesthesing them, 3 square cm diameter skin lesion on the back of each of them was made. Then, the mummify solution (18.3g/dl) and phenytoin cream (1%) were used locally on mummify and phenytoin groups. The control group did not receive any drug. Surface of the lesion and percentage of wound healing were measured in the days 1, 4, 7, 10, 13, 16, 19 and 22 and the time of complete healing was determined. Furthermore, the antibacterial effect of some concentrations of mummify in culture was studied.FINDINGS: The surface of wound among mummify group in comparison to phenytoin and control groups, and also in phenytoin group in comparison to control group in the 4 day was significantly decreased (p<0.05). The surface of wound between mummify and control groups at 10th day and between phenytoin and mummify groups at 13th day had a significant difference (p<0.05). In the day of 10, percentage of wound healing for mummify and phenytion groups were about 20% and in the day of 13 was 30% more than the control group (p<0.05). The time for complete wound healing in mummify and phenytoin groups were 5.4 and 4.4 days less than the control group, respectively (p<0.05). As well, mummify had a complete inhibitory effect on pseudomonas aeroginosa.CONCLUSION: Mummify solution accelerates skin wound healing and it can be compared with phenytoin cream (1%). Also, it had a complete inhibitory effect on the growth of pseudomonas aeroginosa.

BACKGROUND AND OBJECTIVE: Hepatitis B vaccination is one of the effective way to prevent and control this disease. With regard to its importance in children and intervention of different factors in vaccine efficacy, this study was done to determine the role of birth weight in production of anti HBS after routine programming of vaccination in our country.METHODS: This analytical study was performed on 120 children under 7 years old who referred to Amirkola children hospital during 2000-2001. They were divided into two groups: low birth weight or ≤2500 gr (group A) and normal birth weight or more than 2500gr (group B). FINDINGS: From all studied children, 40 cases were in group A (25 males and 15 females) and 80 cases were in group B (43 males, 35 females and 2 children were excluded). Mean age was almost the same in both groups. In group A, 36 cases (90%) had protective levels of Anti HBS (>10 mIu/ml) and in 4 cases (10%), Anti HBS levels were less. In group B, the protective levels of Anti HBS had been produced in all of the children (p=0.012). But, there was not a significant difference between protective levels of Anti HBS in group A and expected response in children (95%). The mean of Anti HBS levels in group A was 182.1±45.1 mIu/mL and in group B was 334.7±41.4 mIu/mL (p=0.014). CONCLUSION: The protective levels of AntiHBS in low birth weight group were lower than normal birth weight group. Since, there was not a significant difference between this response in LBW and ideal response in children, it is recommended to continue routine vaccination in LBW like normal birth weight infants.

BACKGROUND AND OBJECTIVE: The aim of this study was to assess the follicular response in induction of ovulation with the use of low dose human menopausal gonadotropin (HMG) in patients with clomiphene citrate resistant PCOs. METHODS: This semi-experimental study was performed on 12 patients with clomiphene citrate resistant PCOs in Fathemeh Zahra infertility center. Induction ovulation was started with 37.5 (IU) of HMG daily and then was increased by 75 IU according to follicular response. Patients were exactly monitored by vaginal sonography. FINDINGS: Eight patients showed suitable follicular response to induction, of whom 2 conceived. In 4 patients, their cycles had cancelled because no follicular response was observed in spite of increasing dose to 75 IU until midcycle. Ovarian hyper stimulation syndrome (OHSS) was not observed in any of them.CONCLUSION: Administration of low dose HMG can be used successfully to stimulate follicular growth in patients with clomiphene citrate resistant PCOs.

BACKGROUND AND OBJECTIVE: The third stage of labour is probably the most dangerous stage, due to bleeding threatens mother. The objective of this study was to determine the effect of early and late cord umbilical clamping and injection of oxytocin after delivery on duration of third stage and hemorrhage and prevalence of retained placenta. METHODS: This study was done on 260 singleton deliveries. Gestations less than 34 weeks, newborns with low birth weight (less than 2000 gr) and fetal distress and also the Rh negative mothers were all excluded from the study. Third stage of labour was managed by three methods. FINDINGS: Duration of the third stage in method 1, 2 and 3 were 8.5±1.8, 3.6±1.9 and 4.2±1.9 minutes, respectively which there was only a significant difference between method 1 and 2 (p<0.05). In method 1, retained placenta was seen in 4 cases (3.5%). In method 1, 2 and 3, the average of hemorrhage in the third stage and standard deviation was 90.3±126, 72±63 and 54.9±70 ml, respectively which there was a significant difference between method 1 and 3 but there was no significant difference between 1 with 2 and 2 with 3. CONCLUSION: According to the results, early umbilical cord clamping is not recommended in order to reduce the duration of the third stage and also the amount of hemorrhage.

BACKGROUND AND OBJECTIVE: Gout is a condition characterized by acute arthritis and hyperuricemia, but the prevalence of hyperuricemia and the level of serum uric acid (SUA) in acute gout is not known exactly. The present study was performed to determine the frequency of hyperuricemia in patients with gout and to compare the SUA level in acute gouty arthritis with control group. METHODS: SUA level during the acute gouty arthritis diagnosed according to clinical criteria was measured by an enzymatic method in the fasting state and compared with age and sex matched controls. The frequency of hyperuricemia (SUA>7 mg/dl) was also determined during the acute gout attack.FINDINGS: 57 patients (50 males, 7 females) and 57 controls (50 males, 7 females) were studied. The mean age of patients and control group were 54±16 years and 56±14 years, respectively. The mean of SUA level in patients were significantly more than controls (8.5±1.8 and 5.3±1 mg/dl respectively, p<0.0001). Hyperuricemia was found in 75.5% of patients during the acute gout attack. In patients without hyperuricemia, the mean of SUA level was 6.4±0.6 mg/dl that was significantly more than controls (p<0.001).CONCLUSION: Acute gouty arthritis is not always associated with hyperuricemia but the SUA level remains high in the majority of patients during the acute attacks.

BACKGROUND AND OBJECTIVE: The prevalence of thumb sucking is different in various societies according to their socio-economic condition. The objective of this study was to evaluate the prevalence of this habit and its effect on dentoalveolar abnormality in Babol. METHODES: This study was performed on 374 children aged 5-6 years old in public and private kindergarten in Babol. Data was gathered by 2 questionnaires and then they were statistically analysed by chi-square test.FINDINGS: Among 374 children, 20.1% had thumb sucking and there was not any significant relationship between boys and girls. Also, overjet (74.7%), open bite (48%), cross bite (54.7%), tongue thrust (56%), and deep and narrow palate (42.7%) were more prevalent in thumb sucker group.CONCLUSION: With regard to high prevalence of thumb sucking in this community and results of this habit, it seems that giving more information to parents about etiologic factors, how to quit this habit and early treatment can be effective for prevention and limitation of other abnormalities.

BACKGROUND AND OBJECTIVE: About 3-5% of Iranian general population is carriers of hepatitis B virus and about 15% of infected persons will be prone to chronic hepatitis and get cirrhosis and primary liver carcinoma. Up to now no therapeutic regimen has been introduced to eradicate completely this infection. The objective of this study was to evaluate immunity status of health care staff of Amirkola children hospital. METHODS: This cross- sectional study was performed on 153 health care personnel of Amirkola children hospital (Babol). At first, a questionnaire included information about the time and number of vaccination was completed. Anti-HBC, Anti-HBS and HBSAg were examined by Radim (ELISA method).FINDINGS: From 150 subjects, 132 (88%) of them were vaccinated against hepatitis B and 18 (12%) had no positive history of vaccination. Also, 6 cases were excluded due to their Anti HBC positive results. The mean age of studied cases was 28.5±8.3 years. On average, 3.8±2 dosage of vaccine was received by subjects. The time interval after the last vaccination was 3.9 ±1.98 years. With consideration of Anti HBS= 10 mIu/ml as a cut- off value, 68.6% of subjects were immunized against hepatitis B and the mean titer of Anti HBS was 263.9± 391.3 mIu/ml. CONCLUSION: According to the results and decrease of immunity in 31.4% of health care personnel who were vaccinated against hepatitis B, it is suggested Anti HBS titer should be examined 2-3 months after vaccination and Anti- HBS titer in immunized patients be controlled every 5-7 years and then booster vaccine be injected after reducing Anti-HBS titer to below protective level

BACKGROUND AND OBJECTIVE: Hydatidiform mole characterized by hydropic swelling and proliferation of chronic villi. Its incidence is various in different parts of the world. It is an emergency and high risk state in pregnancy. This study was done to determine the prevalence of hydatidiform mole and its clinical manifestation and complication in patients who referred to us.METHODS: This study was performed on 12069 pregnant women who referred to Babol Yahyanejad hospital during 1996-2000. Data of their files was gathered and recorded in a questionnaire and then was arranged for this report. FINDINGS: Forty molar pregnancies were diagnosed. 75% of the cases were 17-30 years old. The most important symptoms were vaginal bleeding (95%), anemia (15%), excessive uterine size (50%), small uterine size (25%), appropriate size (25%), hyperemesis gravidarum (25%), hyperthyroidism (2.5 %). Pre-eclampsia and pulmonary emboli were not seen. CONCLUSION: Considering clinical manifestation and early sonography in pregnancy due to an early diagnosis and reduce its complication and progress of persistent trophoblastic disease, are recommended.

BACKGROUND AND OBJECTIVE: Intertrochanteric fracture which occurs in intertrochanteric line is very common among elderly ages with slight and severe trauma. There are several forms of treatment of this fracture. The aim of this study was to evaluate the treatment of these fractures by DHS in Babol. METHODS: This study was conducted on 100 patients (55% males, 45% females) with intertrochanteric fractures referred to the hospitals of Babol town during 1997-2002. The age ranged between 45 to 85 years and patients with fracture of other limbs were excluded. All individuals were operated by DHS and followed up for one year. FINDINGS: 55% and 45% of cases had unstable and stable fractures, respectively. After surgery, complication occurred in 12% of patients, and 30% of cases were died after discharge from the hospital. Eighty-eight of cases were treated by DHS and the results of treatment were satisfactory. This success was equal between sexes.CONCLUSION: According to the results, this method in treatment of intertrochanteric fracture in comparison to other methods was satisfactory. Therefore, it is suggested all patients with this kind of fracture be treated by DHS.

BACKGROUND AND OBJECTIVE: The congenital anomaly of nose is the one of causes of cosmetic of face and repair of this defect is very difficult. In this article, it was reported a case of congenital hypo plastic nasal alar with failure in operation two times. CASE: A 19 year old female referred with hypo plastic nasal alar who had been already operated two times with a failure in repairing this defect. A composite graft from ear with suitable size was inserted in the defect area of nose and it was improved. CONCLUSION: For repairing this anatomical defect and decreasing failure, this new surgical method is suggested.