In this article, the bases and principles have been considered as the first origins and fundamental principles of every science. In this regard, we encounter with this question that the supreme political wisdom would be consistent of which philosophical principles and bases (fundamental epistemology, ontology, anthropology, and methodology).To get the answer, it should be compared the bases of supreme political wisdom with those of common and secular political philosophies as well as positivist, comprehensible, phenomenological- hermeneutic methodologies plus the critical realism method of Frankfurt circle to illuminate the common facets, differences and priorities of this wisdom.This article claims that utilizing a variety of bases and insightful sources such as revelation, intuition, intellect and sense, along with the ontological and anthropological principles, a fundamental method for the creation of a supreme political wisdom providing the mans’ political-social life through the intellectual statement as well as their happiness here after could be easily developed.In a comparison between the theoretical bases of supreme political wisdom with those of political philosophies or the common and secular politics, it has been stated the potentialities of the supreme wisdom along with more attention to the superiorities and benefits. Thus, the theoretical bases of supreme political wisdom would be considered as fundamental elements for its creation.