Central Asia has been characterized by some regional disputes and tensions including the securitization of border and territorial disputes, water and environment issues, ethnic and linguistic identities, communication corridors and energy transmission lines for more than two decades. However, it has gradually entered a new era of detente and de-securitization since a decade ago that is the transformation of an issue from an urgent political situation into a normal one. This trend has intensified in the past decade with the new generation of regional leaders and the normalization of Tajikistan-Uzbekistan relations. As a result of these developments, many issues such as water, environment, borders and crossings, communication corridors and energy transmission lines, have been gradually taken out of their past securitized situation and have entered into a normal one. The present literature addresses the question that what causes and contexts have led to the dé tente and de-securitization in Central Asia? In order to reply the mentioned question, the hypothesis can be put forward that "the advent of a new generation of Central Asian leaders as securitizing actors, the new discourse of new leaders and elites, the shared benefits of expanding energy transmission lines and communication and transit corridors as well as common water and environmental threats, have led to detente and de-securitization in Central Asia". In order to evaluate the proposed hypothesis, the author attempts to provide a better understanding of the new developments taking place in Central Asia by applying the theoretical concepts and components of securitization and de-securitization as presented in Copenhagen security school.