Extraction of thebaine from Papaver bracteatum Lindl. Capsule using supercritical fluid CO2

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Ashrafkhorasani M.; RAOFIE F.

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

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Paper Information

Journal: IRANIAN JOURNAL OF MEDICINAL AND AROMATIC PLANTS Year:2016 | Volume:32 | Issue:3 (77) Page(s): 459-470

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Information Journal Paper

Title

Extraction of thebaine from Papaver bracteatum Lindl. Capsule using supercritical fluid CO2

Author(s)

Ashrafkhorasani M. | RAOFIE F. | Issue Writer Certificate

Keywords

Papaver bracteatum Lindl.Q1

thebaineQ2

super critical fluidQ3

extractionQ2

Abstract

Papaver bracteatum Lindl. is an Iranian native plant. Papaver bracteatum has red flowers and deep leaves; the end of leaves close to sepals is black in color. The plant has a length of 20 to 120 centimeter, growing wild in nature. The capsules of this plant contain thebaine. thebaine can be converted to different types of painkiller in a simple reaction. In this project for the first time, thebaine was extracted from Papaver bracteatum using super critical fluid with high efficiency. The extracted thebaine was separated and identified using high performance liquid chromatography with UV detector (HPLC-UV). To optimize the extraction condition, a central composite design was used after a 2n-1 fractional factorial design. This model predicted the extraction conditions i. e. 350 atm pressure, 35◦ C temperature, static and dynamic time of 10 min and 40 min, respectively, and 100μ L volume of modifier (ethanol). Under optimum condition, the efficiency of extraction was predicted to be 2. 96%.

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APA: Copy

Ashrafkhorasani, M., & RAOFIE, F.. (2016). Extraction of thebaine from Papaver bracteatum Lindl. Capsule using supercritical fluid CO2. IRANIAN JOURNAL OF MEDICINAL AND AROMATIC PLANTS, 32(3 (77) ), 459-470. SID. https://sid.ir/paper/105213/en

Vancouver: Copy

Ashrafkhorasani M., RAOFIE F.. Extraction of thebaine from Papaver bracteatum Lindl. Capsule using supercritical fluid CO2. IRANIAN JOURNAL OF MEDICINAL AND AROMATIC PLANTS[Internet]. 2016;32(3 (77) ):459-470. Available from: https://sid.ir/paper/105213/en

IEEE: Copy

M. Ashrafkhorasani, and F. RAOFIE, “Extraction of thebaine from Papaver bracteatum Lindl. Capsule using supercritical fluid CO2,” IRANIAN JOURNAL OF MEDICINAL AND AROMATIC PLANTS, vol. 32, no. 3 (77) , pp. 459–470, 2016, [Online]. Available: https://sid.ir/paper/105213/en

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