PREPARATION AND ANALYSIS OF THE PROPERTIES OF CALCIUM PHOSPHATE CEMENT LOADED WITH GENTAMYCINE SULFATE DRUG

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HAGHBIN NAZARPAK M.; SOULATI HASHJIN M.; MOZTARZADEH F.; MIRHABIBI A.R.

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Journal: AMIRKABIR Year:2007 | Volume:18 | Issue:66-A Page(s): 75-80

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Title

PREPARATION AND ANALYSIS OF THE PROPERTIES OF CALCIUM PHOSPHATE CEMENT LOADED WITH GENTAMYCINE SULFATE DRUG

Author(s)

HAGHBIN NAZARPAK M. | SOULATI HASHJIN M. | MOZTARZADEH F. | MIRHABIBI A.R. | Issue Writer Certificate

Keywords

CALCIUM PHOSPHATE CEMENTQ3

GENTAMYCINE SULFATEQ3

DRUG RELEASEQ2

Abstract

CALCIUM PHOSPHATE CEMENTs are widely used in repairing bone and dental defects recently. These cements exhibit excellent biocompatibility and osteoconductivity. In this research, CALCIUM PHOSPHATE CEMENTs are prepared with the ratio of 1/p=OA by mixing powder components consists of Na2SO4, b-TCP, MCPM and liquid component Na2HPO4 (4 weight percent concentration). The initial setting time was equal to 7 minutes and the final setting time is 20 minutes. The compressive strength of samples is measured in different times of incubation. Then, the GENTAMYCINE SULFATE drug is added to liquid component with concentration of 80mg/2ml in ratio of 1/6. The results imply that the initial and final setting time of samples are decreased to 5 and 15 minutes, respectively due to the presence of sulfate ion in the drug. However, compressive strength of samples increased after drug addition. Microstructure of the fracture surface is studied with scanning electron microscope (SEM). The amount of the DRUG RELEASEd in ringer solution is measured within different incubation times. The analysis revealed the fact that the amount of the DRUG RELEASE reached its maximum value in 15th day that is 35% of its primary value.

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APA: Copy

HAGHBIN NAZARPAK, M., SOULATI HASHJIN, M., MOZTARZADEH, F., & MIRHABIBI, A.R.. (2007). PREPARATION AND ANALYSIS OF THE PROPERTIES OF CALCIUM PHOSPHATE CEMENT LOADED WITH GENTAMYCINE SULFATE DRUG. AMIRKABIR, 18(66-A), 75-80. SID. https://sid.ir/paper/1078/en

Vancouver: Copy

HAGHBIN NAZARPAK M., SOULATI HASHJIN M., MOZTARZADEH F., MIRHABIBI A.R.. PREPARATION AND ANALYSIS OF THE PROPERTIES OF CALCIUM PHOSPHATE CEMENT LOADED WITH GENTAMYCINE SULFATE DRUG. AMIRKABIR[Internet]. 2007;18(66-A):75-80. Available from: https://sid.ir/paper/1078/en

IEEE: Copy

M. HAGHBIN NAZARPAK, M. SOULATI HASHJIN, F. MOZTARZADEH, and A.R. MIRHABIBI, “PREPARATION AND ANALYSIS OF THE PROPERTIES OF CALCIUM PHOSPHATE CEMENT LOADED WITH GENTAMYCINE SULFATE DRUG,” AMIRKABIR, vol. 18, no. 66-A, pp. 75–80, 2007, [Online]. Available: https://sid.ir/paper/1078/en

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